“…These results indicate that viruses from the same family, impact ADAR1 functions in different ways. Indeed, herpesvirus transcriptome studies, although limited in number and comprehensiveness, show hyper-editing of transcripts that are not conserved, neither in sequence nor function, between different herpesviruses [33]. For instance, selective editing was found for non-conserved miRNAs encoded by KSHV [40,41], EBV [42,43] and HSV-1 [44,45], while on the other hand, editing of host miR-376a was found to be important for HCMV infection [39].…”