RNA to Rule Them All: Critical Steps in Lassa Virus Ribonucleoparticle Assembly and Recruitment

Overview of the 2023 Physical Virology Gordon Research Conference—Viruses at Multiple Levels of Complexity

“…In many virus families, the formation of an infectious virus requires that hundreds or thousands of proteins co-assemble with other components, without external guidance or control, into a particular three-dimensional structure [ 1 ]. Viral particles must exit a host cell during or after assembly [ 2 ], target and infect new cells, and hijack the machinery of infected cells to manufacture the components for new viral particles [ 3 , 4 , 5 , 6 , 7 ]. Some viruses completely redesign the interior of their host cell, creating new compartments and complex processes to transport components [ 8 , 9 , 10 , 11 , 12 , 13 , 14 ].…”