Road traffic noise, blood pressure and heart rate: Pooled analyses of harmonized data from 88,336 participants

Zijlema, Wilma L.; Cai, Yutong; Doiron, Dany; Mbatchou, Stéphane; Fortier, Isabel; Gulliver, John; Hoogh, Kees de; Morley, David; Hodgson, Susan; Elliott, Paul; Key, Timothy J.; Kongsgård, Håvard Wahl; Hveem, Kristian; Gaye, Amadou Thierno; Burton, Paul; Hansell, Anna; Stolk, Ronald P.; Rosmalen, Judith

doi:10.1016/j.envres.2016.09.014

Cited by 33 publications

(28 citation statements)

References 41 publications

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“…First, our results suggest that, where both noise and air pollution are independently associated with an acute cardiovascular outcome, neither pollutant completely explains the effect of the other. These findings corroborate results from several previous studies of concurrent exposure to traffic noise and air pollution on cardiovascular outcomes including prevalent hypertension and blood pressure 16 – 18 , heart rate 17 , incident myocardial infarction 19 , hospital readmission for myocardial infarction 20 , all-cause mortality 20 , heart failure 7 , myocardial infarction mortality 21 and CHD mortality 8 . These studies and others examining correlations between traffic noise and air pollution 22 , 23 were the first to suggest that noise may confound traffic-related health effects in epidemiologic studies of air pollution, and we assessed this potential bias more precisely by using personal exposure measures.…”

Section: Discussionsupporting

confidence: 90%

Acute cardiovascular health effects in a panel study of personal exposure to traffic-related air pollutants and noise in Toronto, Canada

Biel

Danieli

Shekarrizfard

et al. 2020

Sci Rep

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Urban populations are often simultaneously exposed to air pollution and environmental noise, which are independently associated with cardiovascular disease. Few studies have examined acute physiologic responses to both air and noise pollution using personal exposure measures. We conducted a repeated measures panel study of air pollution and noise in 46 non-smoking adults in Toronto, Canada. Data were analyzed using linear mixed-effects models and weighted cumulative exposure modeling of recent exposure. We examined acute changes in cardiovascular health effects of personal (ultrafine particles, black carbon) and regional (PM2.5, NO2, O3, Ox) measurements of air pollution and the role of personal noise exposure as a confounder of these associations. We observed adverse changes in subclinical cardiovascular outcomes in response to both air pollution and noise, including changes in endothelial function and heart rate variability (HRV). Our findings show that personal noise exposures can confound associations for air pollutants, particularly with HRV, and that impacts of air pollution and noise on HRV occur soon after exposure. Thus, both noise and air pollution have a measurable impact on cardiovascular physiology. Noise should be considered alongside air pollution in future studies to elucidate the combined impacts of these exposures in urban environments.

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Section: Discussionsupporting

confidence: 90%

Acute cardiovascular health effects in a panel study of personal exposure to traffic-related air pollutants and noise in Toronto, Canada

Biel

Danieli

Shekarrizfard

et al. 2020

Sci Rep

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show abstract

“…Further, there are many ways in which physical environments can obscure information needed for safety, including distortion of information, for example by darkness, dense fog, or loud noise. Continuous noise such as road traffic noise leads to chronic physiological stress activity [ 167 , 168 , 169 ], also during sleep [ 167 ], and increased risks for cardiovascular disease [ 170 , 171 ]. Noise has often been used in stress experiments, and we take it for granted that loud, sustained noise can be used as a stressor.…”

Section: Compromised Domains: Prolonged Stress Responses Without Smentioning

confidence: 99%

Generalized Unsafety Theory of Stress: Unsafe Environments and Conditions, and the Default Stress Response

Brosschot

Verkuil

Thayer

2018

IJERPH

159

164

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Prolonged physiological stress responses form an important risk factor for disease. According to neurobiological and evolution-theoretical insights the stress response is a default response that is always “on” but inhibited by the prefrontal cortex when safety is perceived. Based on these insights the Generalized Unsafety Theory of Stress (GUTS) states that prolonged stress responses are due to generalized and largely unconsciously perceived unsafety rather than stressors. This novel perspective necessitates a reconstruction of current stress theory, which we address in this paper. We discuss a variety of very common situations without stressors but with prolonged stress responses, that are not, or not likely to be caused by stressors, including loneliness, low social status, adult life after prenatal or early life adversity, lack of a natural environment, and less fit bodily states such as obesity or fatigue. We argue that in these situations the default stress response may be chronically disinhibited due to unconsciously perceived generalized unsafety. Also, in chronic stress situations such as work stress, the prolonged stress response may be mainly caused by perceived unsafety in stressor-free contexts. Thus, GUTS identifies and explains far more stress-related physiological activity that is responsible for disease and mortality than current stress theories.

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“…This is also in line with the literature. In their cohort study, Sørensen et al found that in the subsample of people with prior diagno- 42 . All these results are most likely due to exposure misclassifi cation or other methodological limitations.…”

Section: Findings On Noise and Blood Pressurementioning

confidence: 99%

Community Noise Exposure and its Effect on Blood Pressure and Renal Function in Patients with Hypertension and Cardiovascular Disease

Dzhambov¹,

Tokmakova²,

Gatseva³

et al. 2017

Folia Medica

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Citation: Dzhambov AM, Tokmakova MP, Gatseva PD, Zdravkov NG, Gencheva DG, Ivanova NG, Karastanev KI, Vladeva SV, Donchev AT, Dermendzhiev SM. Community noise exposure and its eff ect on blood pressure and renal function in patients with hypertension and cardiovascular disease.Folia Medica 2017;59(3): 344-356. doi: 10.1515/folmed-2017-0045 Background: Road traffi c noise (RTN) is a risk factor for cardiovascular disease (CVD) and hypertension; however, few studies have looked into its association with blood pressure (BP) and renal function in patients with prior CVD. Aim: This study aimed to explore the eff ect of residential RTN exposure on BP and renal function in patients with CVD from Plovdiv Province. Materials and methods:We included 217 patients with ischemic heart disease and/or hypertension from three tertiary hospitals in the city of Plovdiv (March -May 2016). Patients' medical history, medical documentation, and medication regimen were reviewed, and blood pressure and anthropometric measurements were taken. Blood samples were analyzed for creatinine, total cholesterol, and blood glucose. Participants also fi lled a questionnaire. Glomerular fi ltration rate was estimated using the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation. All participants were asked about their annoyance by diff erent noise sources at home, and those living in the city of Plovdiv (n = 132) were assigned noise map L den and L night exposure. The eff ects of noise exposure on systolic blood pressure (SBP), diastolic blood pressure (DBP), and estimated glomerular fi ltration rate (eGFR) were explored using mixed linear models. Results: Traffi c noise annoyance was associated with higher SBP in the total sample. The other noise indicators were associated with non-signifi cant elevation in SBP and reduction in eGFR. The eff ect of L den was more pronounced in patients with prior ischemic heart disease/stroke, diabetes, obesity, not taking Ca-channel blockers, and using solid fuel/gas at home. L night had stronger eff ect among those not taking statins, sleeping in a bedroom with noisy façade, having a living room with quiet façade, and spending more time at home. The increase in L den was associated with a signifi cant decrease in eGFR among men, patients with ischemic heart disease/stroke, and those exposed to lower air pollution. Regarding L night , there was signifi cant eff ect modifi cation by gender, diabetes, obesity, and time spent at home. In some subgroups, the eff ect of RTN was statistically signifi cant. Conclusions: Given that generic risk factors for poor progression of cardiovascular diseases cannot be controlled suffi ciently at individual level, environmental interventions to reduce residential noise exposure might result in some improvement in the management of blood pressure and kidney function in patients with CVD.

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Road traffic noise, blood pressure and heart rate: Pooled analyses of harmonized data from 88,336 participants

Abstract: Introduction

Cited by 33 publications

References 41 publications

Acute cardiovascular health effects in a panel study of personal exposure to traffic-related air pollutants and noise in Toronto, Canada

Acute cardiovascular health effects in a panel study of personal exposure to traffic-related air pollutants and noise in Toronto, Canada

Generalized Unsafety Theory of Stress: Unsafe Environments and Conditions, and the Default Stress Response

Community Noise Exposure and its Effect on Blood Pressure and Renal Function in Patients with Hypertension and Cardiovascular Disease

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