This study aims to compare posterior retroperitoneal laparoscopic adrenalectomy (PRLA) and laparoscopic transperitoneal adrenalectomy (LTA) in adults using pan-European data as con icting results have been published regarding length of hospital stay, institutional volume, and morbidity.
MethodsThis retrospective cohort study analyzed data from the surgical registry EUROCRINE ® . All patients undergoing PRLA and TLA for adrenal tumours and registered between 2015 and 2020 were included and compared for morbidity, length of hospital stay, and conversion to open surgery.
ResultsA total of 2,660 patients from 11 different countries and 69 different hospitals were analyzed and 1,696 LTA were compared to 964 PRLA. Length of hospital stay was shorter after RPLA, with less patients (N=434, 45.5%, vs N=1094, 65.0%, p<0.001) staying more than 2 days. In total, 96 patients (3.6%) developed a complication Clavien-Dindo grade 2 or higher. No statistical difference was found between both study groups. After propensity score matching, length of hospital stay was shorter after PRLA (>2 days 45.2% vs 63.0%, p<0.001). After multivariable logistic regression, factors associated with morbidity were age (OR 1.03), male sex (OR 1.52), and conversion to open surgery (OR 5.73).
ConclusionThis study presents the largest retrospective observational analysis comparing LTA and PRLA. Our ndings con rm the shorter length of hospital stay after PRLA. Both techniques are safe leading to comparable morbidity and conversion rates.