Robot-assisted ureteral reconstruction using a tubularized peritoneal flap: a novel technique in a chronic porcine model

Abstract

Robot-assisted ureteral reconstruction using a tubularized peritoneum flap is technically feasible and reproducible. The flap sustained abundant vascular supply after different intervals of follow-up and the peritoneal mesenchymal cells differentiated into urothelium and myofibroblasts. Further studies are needed to address the issue of functional obstruction to improve long-term renal function outcomes.

Tissue-engineered autologous peritoneal grafts for bladder reconstruction in a porcine model

“…After 10 weeks, histological examination showed that the constructed ureteral lumens were lined with transitional epithelium. Brandao et al 22 performed robotic ureteral reconstruction with a tubularized peritoneal flap in six pigs and reported focal urothelial lining of the neoureter. In our study, we removed the entire bladder and replaced it with a neobladder assembled from the peritoneal sheet and the seromuscular layer of the ileum.…”

Editorial Comment from Dr Goel to Total proximal ureter substitution using buccal mucosa

“…In an interesting article, Brandao et al . reported the use of a tubularized peritoneal flap to bridge an artificially‐created ureteral defect in an animal model . Although they reported technical feasibility, they noted significant shrinkage in the length and width of the flap.…”