Robotic extralevator excision of a retrorectal giant aggressive angiomyxoma

Kelley, Scott R.

doi:10.5468/ogs.2018.61.6.693

Cited by 6 publications

(4 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…4,9 The current standard of treatment involves wide surgical excision with negative margins. [10][11][12] This article aims to present a 35-year experience managing AAs of the pelvis.…”

Section: Principales Medidas De Resultadomentioning

confidence: 99%

Aggressive Angiomyxoma of the Pelvis: 35-year Experience

Cardenas Lara,

Bauzon,

Perry

et al. 2023

Diseases of the Colon &Amp; Rectum

Self Cite

View full text Add to dashboard Cite

BACKGROUND: Aggressive angiomyxoma is a very rare mesenchymal tumor most commonly found in the pelvic and perineal regions. Although many are estrogen and progesterone hormone receptor positive, the pathogenesis is unknown. Due to the rarity, there is a paucity of literature relating to this pathology. This paper presents a case-series on the management of aggressive angiomyxoma of the pelvis. OBJECTIVE: To present a 35-year experience managing aggressive angiomyxoma of the pelvis. DESIGN: This was a retrospective single system analysis. SETTINGS: This study was conducted at a quaternary referral academic healthcare system. PATIENTS: All patients treated for aggressive angiomyxoma of the pelvis. INTERVENTIONS: All patients underwent surgical and/or medical management of their disease. MAIN OUTCOME MEASURES: The primary outcomes were disease recurrence and mortality. Secondary outcomes included risk factors for recurrence. RESULTS: A total of 32 patients (94% female) were identified with a median follow-up of 65 months. Thirty (94%) underwent operative resection and 2 were treated solely with medical management. Fifteen achieved an R0 resection (negative microscopic margins) at the index operation, of which 4 (27%) experienced tumor recurrence. There were no mortalities. No risk factors for disease recurrence were identified. LIMITATIONS: Limitations to our study include its nonrandomized retrospective nature, single healthcare system experience, and small patient sample size. CONCLUSIONS: Aggressive angiomyxoma is a rare, slow-growing tumor with locally invasive features and high potential for recurrence even after resection with negative margins. Imaging modalities such as CT and/or MRI should be obtained to aid in diagnosis and surgical planning. Workup should be paired with preoperative biopsy and testing for hormone receptor status, which can increase diagnostic accuracy and guide medical treatment. Close post-treatment surveillance is imperative to detect recurrence. See Video Abstract.

show abstract

“…4,9 The current standard of treatment involves wide surgical excision with negative margins. [10][11][12] This article aims to present a 35-year experience managing AAs of the pelvis.…”

Section: Principales Medidas De Resultadomentioning

confidence: 99%

Aggressive Angiomyxoma of the Pelvis: 35-year Experience

Cardenas Lara,

Bauzon,

Perry

et al. 2023

Diseases of the Colon &Amp; Rectum

Self Cite

View full text Add to dashboard Cite

show abstract

“…AAM is a rare mesenchymal tumor of vulvo-vagina that is slow-growing with a high rate of local recurrence but a low metastatic rate [ 8 ]. It is a benign tumor that is locally aggressive [ 9 ].…”

Section: Discussionmentioning

confidence: 99%

Aggressive Angiomyxoma, Angiomyofibroblastoma, and Cellular Angiofibroma of the Lower Female Genital Tract: Related Entities With Different Outcomes

Haroon¹,

Irshad²,

Zia³

et al. 2022

Cureus

View full text Add to dashboard Cite

IntroductionMesenchymal tumors of the lower female genital tract (FGT) are a miscellaneous group of tumors that include aggressive angiomyxoma (AAM), angiomyofibroblastoma (AMFB), cellular angiofibroma (CAF), and related entities. Histologically, these tumors are composed of stromal cells admixed with vessels, with some minor histological differences. An accurate diagnosis of these tumors is important owing to the differences in the outcome. In this study, we determined the clinicopathological characteristics of these tumors in our population and their association with recurrence. MethodsThis was a retrospective cross-sectional study conducted at the Department of Histopathology, Aga Khan University, from January 2005 to December 2019 over a period of 15 years. A total of 207 cases that were diagnosed as AAM, AMF, and CAF were selected for inclusion in the study. Clinical data, including age and location of the lesion, were obtained from histopathology referral forms. Tissue blocks of all cases were retrieved. Follow-up data were obtained from the patient files, and information regarding disease recurrence was recorded. One histological section from each tissue block was stained with hematoxylin and eosin stain, and histopathological findings were recorded. Additionally, immunohistochemical (IHC) studies, including vimentin, smooth muscle actin (SMA), and desmin were conducted on representative tissue blocks. Final histopathological diagnoses were rendered considering clinical, histopathological, and IHC findings.

show abstract

“…Surgical excision is the standard treatment, and it is especially relevant to acquire negative pathologic margins to reduce the local relapse. 2 We report the case of a 47 year-old woman diagnosed with an aggressive angiomyxoma of the pelvis and perineum. A magnetic resonance imaging (MRI) scan revealed a 9 cm infiltrative mass at the level of the lateral wall of the left introitus, extending to the left infravesical space, lateral wall of the vagina and anal sphincter, infiltrating the levator ani muscle and the ischiorectal fossa.…”

Section: Gynecological Cancermentioning

confidence: 99%

“…Aggressive angiomyxoma is a rare mesenchymal tumor, typically arising in the soft tissue of the pelvis and perineum,1 with local aggressive behavior and frequent local recurrence. Surgical excision is the standard treatment, and it is especially relevant to acquire negative pathologic margins to reduce the local relapse 2…”

mentioning

confidence: 99%