Robotics-assisted modular assembly of bioactive soft materials for enhanced organ fabrication

Kang, Dayoon; Hong, SeungTaek; Kim, Seon-Jin; Choi, Hwanyong; Kim, Keehoon; Jang, Jinah

doi:10.1080/17452759.2024.2390484

Virtual and Physical Prototyping

2024

DOI: 10.1080/17452759.2024.2390484

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Robotics-assisted modular assembly of bioactive soft materials for enhanced organ fabrication

Dayoon Kang,

SeungTaek Hong,

Seon-Jin Kim

et al.

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2024

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Cited by 3 publications

References 169 publications

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Modular strategy with autologous bioreactor: a potential way for organ engineering

Bai,

Tang,

Chen

et al. 2024

Int. J. Extrem. Manuf.

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Bioengineered organs have been seen as a promising strategy to address the shortage of transplantable organs. However, it is still difficult to achieve heterogeneous structures and complex functions similar to natural organs by current bioengineering techniques. This work introduced the methods and dilemmas in organ engineering and existing challenges. Furthermore, a new roadmap for organ engineering, which uses a modular strategy with autologous bioreactors to create organ-level bioengineering constructions, was summarized based on the latest research advances. In brief, different functional modules of natural organs are constructed in vitro, and autologous bioreactors in vivo are utilized to facilitate inter-module assembly to form a complete bioengineered organ capable of replacing natural organ functions. There are bioengineered organs, such as biomimetic tracheas, that have been successfully fabricated following this roadmap. This new roadmap for organ engineering shows promise in addressing the shortage of transplantable organs and has broad prospects for clinical applications.

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Modular strategy with autologous bioreactor: a potential way for organ engineering

Bai,

Tang,

Chen

et al. 2024

Int. J. Extrem. Manuf.

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show abstract

Integrating Robotics in Bioprinting: Advancements in 3D-Printed Tissue and Organ Engineering

Baysal

2024

NFLSAI

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The integration of robotics in bioprinting is revolutionizing the field of tissue and organ engineering, enabling unprecedented precision, scalability, and complexity in 3D-printed biological structures. This research explores the advancements brought about by robotic systems in bioprinting processes, focusing on their role in enhancing the fabrication of tissues and organs with intricate architectures and functional properties. Key areas of investigation include robotic-assisted multi-material deposition, real-time process monitoring, and adaptive printing techniques that ensure high fidelity and cell viability. The study also examines the incorporation of robotics into scalable bioprinting workflows for large-scale tissue engineering and transplantable organ production. Ethical considerations, such as regulatory challenges and equitable access, are addressed to highlight the societal implications of these innovations. By bridging robotics, bioengineering, and regenerative medicine, this research underscores the transformative potential of robotic-assisted bioprinting in addressing critical healthcare challenges, including organ shortages and personalized medicine. With advancements in precision and adaptability, robotic systems are poised to reshape the future of bioprinting, paving the way for breakthroughs in tissue engineering and regenerative therapies.

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Robotic Assisted Organ Transplantation

Ağır

2024

NFLSAI

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Robotic-assisted organ transplantation represents a groundbreaking advancement in surgical medicine, combining precision robotics with minimally invasive techniques to improve patient outcomes and expand the feasibility of complex procedures. This research explores the integration of robotic systems in organ transplantation, focusing on their application in donor organ harvesting, surgical precision, and post-transplantation recovery. Robotic-assisted systems, equipped with enhanced visualization, dexterity, and AI-driven analytics, enable surgeons to perform intricate operations with unparalleled accuracy, reducing the risk of complications and shortening recovery times. The study examines the advantages of robotic platforms in addressing challenges such as limited donor organ availability and improving transplant success rates. Furthermore, it evaluates the ethical considerations, cost implications, and training requirements associated with implementing robotic technologies in transplantation practices. By synthesizing data from clinical trials and case studies, this research underscores the transformative potential of robotics in advancing organ transplantation and reshaping the future of surgical innovation.

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Robotics-assisted modular assembly of bioactive soft materials for enhanced organ fabrication

Cited by 3 publications

References 169 publications

Modular strategy with autologous bioreactor: a potential way for organ engineering

Modular strategy with autologous bioreactor: a potential way for organ engineering

Integrating Robotics in Bioprinting: Advancements in 3D-Printed Tissue and Organ Engineering

Robotic Assisted Organ Transplantation

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