Robust and reliable detection of malondialdehyde in biological samples via microprobe-triggered surface-enhanced Raman spectroscopy

Wu, Zhe; Wang, Yingjie; Wang, Yufei; Zhang, Kaining; Lai, Yongchao

doi:10.1016/j.microc.2022.107815

Cited by 9 publications

(6 citation statements)

References 46 publications

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“…Taking into account possible interferences, MDA, one of the main end products of lipid peroxidation, was considered as a reference. In a recent study [55], the MDA signal by SERS with mixed Au/Ag nanoparticles in the vicinity of 1655 cm −1 , more precisely at 1663 cm −1 used by the authors for the effective measurement of a complex between MDA and 4-aminophenylthiophenol, was negligible. Since lipid peroxidation occurs mainly in unsaturated fatty acids, and double bonds between carbon atoms are lost in the process, the decrease in the peak at 1655 cm −1 can be satisfactorily attributed to lipid peroxidation.…”

Section: Resultsmentioning

confidence: 91%

Innovative Surface-Enhanced Raman Spectroscopy Method as a Fast Tool to Assess the Oxidation of Lipids in Ground Pork

et al. 2023

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A novel method for the determination of lipid oxidation using Raman microscopy was developed. A home-made surface-enhanced Raman spectroscopy (SERS) substrate based on silver nanoparticles deposited on a glass Petri dish was used. The degradation of ground pork stored at 5 °C was monitored for 16 days. Two packages were considered: an active packaging containing an oregano extract with antioxidant properties and a conventional one consisting of a low-density polyethylene (LDPE) film. The lipid fraction of the ground pork was extracted with a mixture of diethyl ether/n-hexane (1:1). A remarkable maximum signal enhancement factor of 1.64 × 107 at 1439 cm−1 shift (and up to 8.58 × 106 at 1655 cm−1, chosen for fat oxidation assessment) was obtained with SERS compared to conventional Raman. In addition, SERS provided better discrimination among samples than the results obtained by the thiobarbituric acid reactive substances (TBARS) method. The experimental conditions for SERS were optimized and discussed.

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Section: Resultsmentioning

confidence: 91%

Innovative Surface-Enhanced Raman Spectroscopy Method as a Fast Tool to Assess the Oxidation of Lipids in Ground Pork

et al. 2023

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“…To explore whether •OH was consumed by reacting with modified Lip, thiobarbituric acid (TBA) chromogenic method was utilized to detect the production of lipid peroxides by UV–vis spectrophotometer. Malondialdehyde (MDA) is a commonly indicator for LPO detection, which can react with TBA in the temperature more than 95 °C and form red MDA-TBA adduct with characteristic absorption peak at 539 nm under acidic condition [ 47 ]. As shown in Fig.…”

Section: Resultsmentioning

confidence: 99%

Liposome encapsulated polydopamine nanoparticles: Enhancing ferroptosis and activating hypoxia prodrug activity

Guo,

Luo,

Jiang

et al. 2024

Materials Today Bio

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“…[9] In addition, SERS technology has been also used to detect other key biological molecules related to various physiological or pathological events in human body. [67][68][69][70] For instance, Wu et al displayed a ratiometric SERS biosensor consisted of DNAmodified metal organic frameworks (MOFs) and gold nanoflowers (GNFs) for ATP analysis (Figure 2D). In this SERS biosensor, toluidine blue (TB), as a Raman reporter, was packaged into MOFs micropores via decorating DNA Y-junctions composed of single-stranded DNA (S1), ATP aptamer (S2), and cDNA on MOF surface.…”

Section: Small Moleculementioning

confidence: 99%

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

Chen

Zheng

Tang

et al. 2023

Chemistry An Asian Journal

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Timely and powerful diagnostic means can achieve better therapeutic effects, reduce disease torment, and improve survival rate. As a powerful non‐invasive spectroscopy technology, surface‐enhanced Raman scattering (SERS) have testified to be a great potential candidate for extensive early clinical disease diagnosis. In recent years, the introduction of SERS label, combined with other analysis modes or artificial intelligence, and the emergence of miniaturized devices have made SERS technology more advantageous in early diagnosis of diseases. This review focuses on the research progress of SERS dominated analytical strategies in the field of early disease diagnosis in the past five years. The main content includes the application of label‐free SERS detection; the construction of label SERS methodologies for various disease markers; SERS dominated multimode early disease diagnosis strategies; integration of SERS and artificial intelligence; portable Raman equipment and SERS imaging; and opportunities and trends for SERS diagnostic technology in the future.

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Robust and reliable detection of malondialdehyde in biological samples via microprobe-triggered surface-enhanced Raman spectroscopy

Cited by 9 publications

References 46 publications

Innovative Surface-Enhanced Raman Spectroscopy Method as a Fast Tool to Assess the Oxidation of Lipids in Ground Pork

Innovative Surface-Enhanced Raman Spectroscopy Method as a Fast Tool to Assess the Oxidation of Lipids in Ground Pork

Liposome encapsulated polydopamine nanoparticles: Enhancing ferroptosis and activating hypoxia prodrug activity

Recent Research Progress of Surface‐Enhanced Raman Scattering Dominated Analysis Strategies in Early Diagnosis of Diseases

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