Cellular networks such as 4G, 5G and beyond are essential components of current and future communication infrastructure. Current research topics such as smart mobility, intelligent transportation systems and autonomous driving heavily depend on the availability of ubiquitous connectivity. In addition, consumer demand for cellular network resources is ever growing. In the context of the InSecTT project, cellular connectivity contributes, e.g., to use cases in the rail domain, where remote monitoring, maintenance and diagnostics rely on the presence of cellular uplinks from the rolling stock to cloud services. As the rolling stock moves, these uplinks are subject to continuously changing conditions that affect the availability and quality of the connection. To counteract this and to increase resilience, onboard systems may be equipped with a number of uplink options that can be used. This chapter discusses the use of AI to assess and manage the available connections and to move data traffic between the available links according to their expected data rates.