In mathematics, to a large extent, control theory addresses the stability of solutions of differential equations, which can describe the behavior of dynamic systems. In this paper, a class of fractional-order nonautonomous systems with multiple time delays modeled by differential equations is considered. A sufficient condition is established for the existence and uniqueness of solutions for such systems involving Caputo fractional derivative, and the uniform stability of solution is studied. At last, two examples are given to demonstrate the applicability of our results.