Medical image watermarking has received extensive attention as wide security services in the healthcare information system. This paper proposes a blind medical image watermarking approach on the segmented gray-matter (GM) images by utilizing discrete wavelet transform (DWT) and discrete cosine transform (DCT) along with enhanced suppressed fuzzy C-means (EnSFCM) for the optimal selection of sub-blocks position to insert a watermark. Experimental results show that the proposed approach outperforms other methods in terms of peak signal to noise ratio (PSNR) and M-SVD. In addition, the proposed approach shows better robustness than other methods in normalized correlation (NC) values against several attacks, such as noise addition, filtering, JPEG compression, blurring, histogram equalization, and cropping.