This paper investigates single-period inventory management problems with uncertain market demand, where the exact possibility distribution of demand is unavailable. In this condition, it is important to order a reliable quantity which can immunize against distribution uncertainty. To model this type of single-period inventory management problem, this paper characterizes the uncertain demand by generalized interval-valued possibility distributions. We present a novel concept about an uncertain distribution set to describe distribution perturbation characterization. First, we introduce a lambda selection of the interval-valued fuzzy variable, and the uncertain distribution set is a collection of all generalized possibility distributions of lambda selection variables. According to the uncertain distribution set, a new distributionally robust fuzzy optimization method is developed for single-period inventory management problems. Under mild assumptions, the robust counterpart of the proposed fuzzy single-period inventory management model is formulated, which is an optimization program with certain linear objectives and infinitely many integral constraints. We discuss the computational issue of integral constraints and reformulate equivalently the robust counterpart as three deterministic inventory submodels under generalized interval-valued trapezoidal possibility distributions. According to the characteristics of three submodels, a domain decomposition method is designed to find the robust optimal solution that can immunize against uncertainty in our single-period inventory management problem. Finally, some computational results demonstrate the efficiency of the proposed distributionally robust fuzzy optimization method.