Objective To assess the effect of systolic data acquisition for electrocardiography (ECG)-triggered high-pitch computed tomography (CT) on motion artefacts of coronary arteries in patients with high heart rates (HRs). Methods Eighty consecutive patients (15 women, age 67± 14years) with HR≥70bpm underwent CT angiography of the thoracic aorta (CTA) on 128-slice dual-source CT in ECG-triggered high-pitch acquisition mode (pitch=3.2) set at 60% (group A, n=40) or 30% (group B, n=40) of the RR interval. Two blinded readers graded coronary artery image quality on a three-point scale. Radiation doses were calculated. Results Interobserver agreement in grading image quality of the 1,154 coronary segments was good (κ=0.62). HRs were similar in groups A and B (85± 13bpm vs 85±14bpm, p not significant). Significantly fewer coronary segments with non-diagnostic image quality occurred (i.e. score 3) in group B than in group A [2.8% (16/ 579) vs 8.3% (48/575), p<0.001]. Seventeen patients (42.5%) of group A and 12 patients (30.0%) of group B had at least one non-diagnostic segment. Effective radiation doses were 2.3±0.3mSv for chest CTA. Conclusion A systolic acquisition window for high-pitch dual-source CTA in patients with high HRs (≥70bpm) significantly improves coronary artery image quality at a low radiation dose.