Roentgen Therapy in Cancer of the Larynx

Lenz, Maurice

doi:10.1001/jama.1947.02880190005002

Cited by 31 publications

(4 citation statements)

References 4 publications

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“…All 82 patients were treated by high dose, megavoltage irradiation with curative intent by either 4.8, 6, or 4 MeV linear accelerators. Precise techniques have been described previously.7 Primary therapy consisted of opposed lateral fields which generally included the first echelon of draining lymphatics.…”

Section: Methodsmentioning

confidence: 99%

Carcinoma of the nasopharynx.Eighteen years' experience with megavoltage radiation therapy

Hoppe

Goffinet

Bagshaw

1976

Cancer

212

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From 1956 through 1973, 82 patients with carcinoma of the nasopharynx received high dose megavoltage radiation therapy at Stanford University. The actuarial disease-free (NED) survival was 62% at 5 years and 56% at 10 years. The NED survivals at 5 years for patients with T1, T2, and T3 lesions were 76%, 68%, and 55%, respectively. No T4 patients were salvaged, but two of 10 patients who presented with cranial nerve dysfunction were long-term survivors. The degree of nodal involvement also had prognostic significance. Involved lymph nodes were successfully controlled in all instances when doses of at least 6500 rads were given. Initial treatment failed in 32 patients. In 24 (75%) this occurred within 18 months. Thirteen patients with initial recurrences in head and neck sites were retreated and three remain alive. Survival after retreatment ranged from 2 months fo 10 years, with a median of 16 months. Although nearly one-third (6/17) of the patients with local recurrences had initial T1 or T2 lesions, there have been no failures in patients treated for these early stages in the last 7 years. This may be attributed to the use of larger treatment fields. Likewise, prophylactic irradiation of the neck was always successful in preventing nodal disease if the primary site was controlled.

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Section: Methodsmentioning

confidence: 99%

Carcinoma of the nasopharynx.Eighteen years' experience with megavoltage radiation therapy

Hoppe

Goffinet

Bagshaw

1976

Cancer

212

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“…Shu Yih and Cowdry" state that it is the most frequent malignancy seen in the Chinese male and the next most frequent in the female in Formosa. Lenz 8 reported an incidence of 6 c /( in his series of 63 cases. At the St. Francis Hospital, for the same period, it was 3.5 9ί -In my own personal experiences, it is by far the most frequent malignancy of the head and neck.…”

Section: Incidencementioning

confidence: 94%

“…Lenz,8 in 1942, reported a 27.6% five year cure in a series of forty-four cases regardless of the stage of the disease. Martin" reported a net five-year cure rate for all patients of 25% in a series of eighty-seven cases.…”

Section: Q Pangmentioning

confidence: 99%

XXVIII Carcinoma of the Nasopharynx An Analysis of Thirty-Four Cases and a Preliminary Report on Palatal Fenestration in its Management

Pang¹

1959

Ann Otol Rhinol Laryngol

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“…It is, however, fair to say that at the junctional rcgion --upper laryngo-pharynx (or epilaryngeal ) growths present more favourable response to radiotherapy, especially when applied to growths which are superficial and not deeply infiltrating. Lenz (1947) reported 28 cases of carcinoma of the epiglottis, in which metastases were present in 21. Nine patients survived for over five years.…”

Section: The Choice Between Surgery and Radiotherapymentioning

confidence: 99%

Surgery of the Laryngo‐pharynx and Cervical Oesophagus

Dunlop

1952

Australian and New Zealand Journal of Surgery

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Summary 1. the difficulties of treatment of carcinomata of the laryngo‐pharynx and cervical 2. reference is made to some misconceptions about treatment and the place of radio therapy and surgery. 3. brief reference is made to pathology, symptomatology and diagnosis. 4. operative treatment is illustrated by methods employed in a personal series of 25 cases, averaging 62 years. 20 major excision operations were carried out, and numerous secondary precedures mainly associated with reconstruction of an artificial pharynx. there was one late post‐operative death. 5. operative methods are discussed, and some account is given of operative results.

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Roentgen Therapy in Cancer of the Larynx

Cited by 31 publications

References 4 publications

Carcinoma of the nasopharynx.Eighteen years' experience with megavoltage radiation therapy

Carcinoma of the nasopharynx.Eighteen years' experience with megavoltage radiation therapy

XXVIII Carcinoma of the Nasopharynx An Analysis of Thirty-Four Cases and a Preliminary Report on Palatal Fenestration in its Management

Surgery of the Laryngo‐pharynx and Cervical Oesophagus

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