Role of 3.0 T MRI in the evaluation of mesial temporal sclerosis using loss of hippocampal striations as diagnostic parameter

Abstract

Background: Mesial Temporal Sclerosis, also known as MTS, is a condition that causes medial temporal lobe epilepsy (MTLE) and is characterized by the loss of hippocampal neurons. Multiple researches on individuals with hippocampal sclerosis (HS) have demonstrated that MRI (magnetic resonance imaging) is an exhaustive method for locating the EF (epileptogenic focus). Aims & Objectives: To study Partial Loss of Hippocampal Striations (PLHS) as a diagnostic parameter using 3.0 Tesla MRI to increase the confidence of diagnosing Mesial Temporal Sclerosis (MTS). Material & methods: This prospective research was performed in 55 patients who had undergone 3T (GE SIGNA HDX) brain imaging under epilepsy protocol that included T2 axial, coronal FLAIR and 3D SPGR hippocampal volume assessment in addition to high resolution T2 coronal imaging over a period of two years at Department of Radiodiagnoses and Imaging (DORAI), Bharat Scans, Chennai, India.