Role of Algal Derived Compounds in Pharmaceuticals and Cosmetics

Mourelle, M. Lourdes; Gómez, Carmen P.; Legido, J.L.

doi:10.1002/9781119542650.ch19

Cited by 7 publications

(3 citation statements)

References 307 publications

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“…Rajauria et al [69] reported that laminarin was screened for its potential antioxidant capacity and found to have a significant radical scavenging capacity against free radicals and metal ions. These results showed that macroalgae are a rich source of natural antioxidants [9,19,53,70] in food and cosmetics [11,21].…”

Section: Antioxidantmentioning

confidence: 81%

“…Laminarin is a relatively underexploited water-soluble polysaccharide present in brown algae that has been reported to exhibit potential therapeutic properties. Laminarin is increasingly being explored for the development of functional food and nutraceuticals [6][7][8][9], as well as a functional material in biomedical applications due to its biodegradable, biocompatible, and non-toxic nature [10,11] (Figure 1). This bioactive compound possesses the therapeutic potential to enhance and promote health and may help protect against diseases, including cardiovascular diseases, metabolic disorders, cancer, diabetes, obesity, anti-inflammatory activity, osteoarthritis, oral diseases, multiple sclerosis, as well as Alzheimer's and Parkinson's diseases, and vision-improving agents [12][13][14][15][16][17].…”

Section: Introductionmentioning

confidence: 99%

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Biological Properties and Health-Promoting Functions of Laminarin: A Comprehensive Review of Preclinical and Clinical Studies

Shanmugapriya

Rajauria

Fitzpatrick³

et al. 2022

Marine Drugs

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Marine algal species comprise of a large portion of polysaccharides which have shown multifunctional properties and health benefits for treating and preventing human diseases. Laminarin, or β-glucan, a storage polysaccharide from brown algae, has been reported to have potential pharmacological properties such as antioxidant, anti-tumor, anti-coagulant, anticancer, immunomodulatory, anti-obesity, anti-diabetic, anti-inflammatory, wound healing, and neuroprotective potential. It has been widely investigated as a functional material in biomedical applications as it is biodegradable, biocompatible, and is low toxic substances. The reported preclinical and clinical studies demonstrate the potential of laminarin as natural alternative agents in biomedical and industrial applications such as nutraceuticals, pharmaceuticals, functional food, drug development/delivery, and cosmeceuticals. This review summarizes the biological activities of laminarin, including mechanisms of action, impacts on human health, and reported health benefits. Additionally, this review also provides an overview of recent advances and identifies gaps and opportunities for further research in this field. It further emphasizes the molecular characteristics and biological activities of laminarin in both preclinical and clinical settings for the prevention of the diseases and as potential therapeutic interventions.

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Section: Antioxidantmentioning

confidence: 81%

Section: Introductionmentioning

confidence: 99%

Biological Properties and Health-Promoting Functions of Laminarin: A Comprehensive Review of Preclinical and Clinical Studies

Shanmugapriya

Rajauria

Fitzpatrick³

et al. 2022

Marine Drugs

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“…algins, carrageenan, and agar) (Holdt and Kraan 2011). In turn, health care researchers are prompted to develop seaweed-based products for the prevention and treatment of diseases (Smit 2004;Rao and Periyasamy 2020;Cotas et al 2021;Mourelle et al 2021).…”

Section: Introductionmentioning

confidence: 99%

Ethnobotany of Medicinal Seaweeds of Ilocos Norte, Philippines

Dumilag¹,

Javier²

2022

Philipp J Sci

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The Ilocano people of Ilocos Norte in the Philippines have high regard for seaweed use. The traditional seaweed medicines used by them are old and time-tested, albeit little explored. This study examines the selection of seaweeds associated with a defined folk knowledge and their source availability in Ilocos Norte. Thirty-four (34) seaweed species were traditionally perceived as medicinal for eight types of emic indications, almost 80% of which were edible. Three major groups, i.e. rhodophytes (16 spp.), ochrophytes (7 spp.), and chlorophytes (11 spp.), of 12 families and 20 genera constituted the list. Most species were used for digestive, pulmonary, and glandular-related complaints. The Ilocano residing Pagudpud and Burgos were the most familiar in terms of the number of used species. Caulerpa racemosa (ar-arusip) was the most familiar seaweed used as a cough or asthma reliever. Caulerpa racemosa, Hydroclathrus clathratus, and Gracilaria edulis had the highest use value, whereas Codium intricatum, Gelidiella acerosa, and C. racemosa had the highest fidelity level scores. The distribution of taxa in dry and wet seasons markedly varied per site. Gelidiella acerosa was the only species growing on all sites year-round. Correspondence between folk use and phytochemical activity was inferred in nearly all listed species. The information presented here will allow continued validations and tests of folk medicinal seaweeds for new drugs and may bring additional armamentarium to the Philippine pharmacopeia.

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