Role of amine activators on the curing parameters, properties and toxicity of acrylic bone cements

Vázquez, Blanca; Levenfeld, B.; Román, Julio San

doi:10.1002/(sici)1097-0126(199807)46:3<241::aid-pi49>3.0.co;2-g

Cited by 64 publications

(39 citation statements)

References 7 publications

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“…However, it is known that secondary and tertiary amines are toxic and carcinogenic to humans, as they may leach into the human body after being used as bone polymers and dentistry polymers. [5][6][7][8][9][10][11][12] To ensure patient safety and regarding green chemistry, these amines should be changed to polyalcohol. With this in mind, this study employed only non-toxic polyalcohols such as glycerol ( (1,2,3-propanetriol), a colorless, odorless, sweetish and very viscous liquid, is a trihidroxylated compound with three carbons, derived from both natural and petrochemical sources.…”

Section: Introductionmentioning

confidence: 99%

Synthesis, thermal studies and conversion degree of dimethacrylate polymers using new non-toxic coinitiators

Alarcon¹,

Holanda²,

Rinaldo³

et al. 2017

Quim. Nova

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The aim of this paper is to replace toxic coinitiators (tertiary amines) by non-toxic compounds such as glycerol and inositol (polyalcohol) in dimethacrylate resins. For this purpose, mid infrared spectroscopy (MIR) was used to calculate the monomers' degree of conversion (%DC); as well as simultaneous Thermogravimetric Analysis -Differential Thermal Analysis (TGA-DTA) and Differential Scanning Calorimetry (DSC) were conducted to evaluate thermal stability, degradation steps, and thermal events. The use of different initiator systems did not modify the thermal events or the thermal stability of each of the dimethacrylate resins. Results show a substitution of system 2 (toxicity) by system 3 (low toxicity), which had a good conversion velocity and total conversion in some monomers, is plausible.

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Section: Introductionmentioning

confidence: 99%

Synthesis, thermal studies and conversion degree of dimethacrylate polymers using new non-toxic coinitiators

Alarcon¹,

Holanda²,

Rinaldo³

et al. 2017

Quim. Nova

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“…In addition, liquid formulations also contain an activator of the polymerization process, which is DMT. By mixing these two components at room temperature, the activator reacts with the thermal inititator generating free radicals ( Figure 2) [16,17]. These radicals react with the double bonds of methacrylate groups of each monomer present in liquid formulations, giving rise to a random polymerization with more EMA and TEGDMA molecules, and finally lead to a crosslinked network ( Figure 3).…”

Section: Of 17mentioning

confidence: 99%

Thermal and Mechanical Characterization of EMA-TEGDMA Mixtures for Cosmetic Applications

Donoso

Reina

Giamberini

et al. 2018

Preprint

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Abstract:Mixtures of methacrylic polymers are the most common materials for making composites to be used as resins for dental and cosmetic applications. Some of these mixtures are composed by poly (ethyl methacrylate) (PEMA) and poly (methyl methacrylate) (PMMA), which constitute a solid component to be mixed with a liquid component made out of methacrylate monomers. The reaction between the thermal initiator benzoyl peroxyde (BPO) present in the solid component and the activator of the polymerization process, N,N-dimethyl-p-toluidine (DMT) present in the liquid component, gives rise to thermoset materials. In the present study, different liquid formulations composed by a mixture of two methacrylic monomers, ethyl methacrylate (EMA) and triethylene glycol dimethacrylate (TEGDMA) for cosmetic applications, were prepared and characterized, using a commercial powder (POW) composed by PEMA and PMMA. With the aim of improving workability during final application of the material, it was necessary to slow down the polymerization rate of liquid formulations. Their thermal behaviour was investigated by DSC in order to check the polymerization rate. Thermal stability of final materials was determined by TGA. DMTA, microindentation hardness and impact tests were performed on final materials, to assess their performance with respect to standard formulation. The combination of thermal and mechanical properties allows choosing which formulations could be suitable for use in cosmetics.

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“…Examples in industry include benzoyl peroxide radicals initiating a process called polymerization that is used as human bone cement and for mending cracks on wings of airplanes [17][18][19][20][21]. In medicine, in vitro studies have demonstrated that benzoyl peroxide radicals have increased antibacterial and antiyeast coverage [18].…”

Section: Benzoyl Peroxide With Alterations As the Preferred Topicalmentioning

confidence: 99%

A Patient-Oriented Approach to Acne, Rosacea, Perioral Dermatitis, and Isotretinoin with Working Patient Informational/Instructional Sheets and a Review of Pathophysiology and Mechanisms of Therapeutic Agents

Burkhart¹

2008

TODJ

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Patient informational/instructional sheets can be used not only to assist in providing patients with baseline material regarding their condition, but also aid in physicians communicating a treatment protocol. Educational material regarding acne, adult acne, perioral dermatitis, and isotretinoin is included for perusal and discussion. Within this framework, one learns the unifying concept of the Propionibacterium acnes biofilm, methods to maximize production of benzoyl peroxide radicals (the active biological form of this compound), unplugging ability of oral antibiotics, and low-dose isotretinoin therapeutics.

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Role of amine activators on the curing parameters, properties and toxicity of acrylic bone cements

Cited by 64 publications

References 7 publications

Synthesis, thermal studies and conversion degree of dimethacrylate polymers using new non-toxic coinitiators

Synthesis, thermal studies and conversion degree of dimethacrylate polymers using new non-toxic coinitiators

Thermal and Mechanical Characterization of EMA-TEGDMA Mixtures for Cosmetic Applications

A Patient-Oriented Approach to Acne, Rosacea, Perioral Dermatitis, and Isotretinoin with Working Patient Informational/Instructional Sheets and a Review of Pathophysiology and Mechanisms of Therapeutic Agents

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