Role of Antibiotic Prophylaxis in Elective Mesh Inguinal Hernioplasty

Santhi, B.; Robert, Kenny; Rengasamy, Sudhagar

doi:10.18410/jebmh/2018/298

Cited by 1 publication

(1 citation statement)

References 14 publications

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“…The bias assessment for each article can be seen in Figure 2. Based on the research articles obtained, the prophylactic antibiotics used consist of six types: cefazolin [10,11,13,14,17,19,[21][22][23]27], Coamoxiclav [8,9,15,25,26], Cefuroxime [16,24,29], Cefotaxime [12,18,30], Ceftriaxone [20,31], and Cloxacillin [28]. A placebo or no antibiotic was used as the comparative control.…”

Section: Bias Assessmentmentioning

confidence: 99%

Meta-Analysis on the effectiveness of the Use of Prophylactic Antibiotics in Preventing Surgical Site Infection in Patients with Hernia Surgery

Wijono,

Kristin,

Peerera

et al. 2023

Advances in Biological Sciences Research

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The administration of prophylactic antibiotics in hernia surgery patients is currently controversial, with varying opinions regarding their necessity. The European Hernia Society guideline does not recommend prophylactic antibiotics in patients with hernia surgery, while recent studies found that prophylactic antibiotics in hernia surgery patients can be given routinely and are effective in reducing surgical site infections. This study aims to determine the effectiveness of prophylactic antibiotics for preventing surgical site infection in patients with hernia surgery. This research is a systematic review using articles with a randomized controlled trial (RCT) research design using Indonesia and English language within the last 10-year of publication year. Twenty-four RCTs that met the inclusion and exclusion criteria were used to address the research problem. The results showed that a total of 207 patients experienced the incidence of surgical site infection in patients with hernia surgery, including 78 patients (4.5%) in the antibiotic group and 129 patients (7.88%) in the control. A significant difference was found between the antibiotic and the control groups in preventing surgical site infections, with a P-value < 0.0001 (OR = 0.56; 95% CI = 0.42 0.75). Conclusion: Surgical site infections are less likely to develop when a prophylactic antibiotic is administered to patients with hernia surgery

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