Role of biobanking in managing large-scale epidemiological studies

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Previous studies have shown significant differences in the health status of the population depending on the place of residence. Despite the ongoing preventive measures, there is no improvement in the epidemiological situation in relation to noncommunicable diseases, including due to unfavorable living conditions. This study is a continuation of the following earlier studies: Epidemiology of Cardiovascular Diseases in Regions of Russian Federation (ESSE-RF) and ESSE-RF-2.Aim. To assess the prevalence of cardiovascular diseases, various risk factors (RFs) of these diseases and their association in Russian regions with different economic, climate and geographic characteristics to determine the risk profile of the region and develop approaches to targeted prevention programs specific to the regions.Material and methods. The study selected 30 regions representing each federal district of the Russian Federation. The survey of participants is carried out in three stages as follows: survey using an original modular questionnaire; measurements, including anthropometry, hand grip strength test, blood pressure and heart rate assessment; blood sampling, followed by biobanking and laboratory tests.Conclusion. The results obtained will allow deepening knowledge about the RF profile specific to a particular region, evaluating the effectiveness of preventive programs, and planning new ones taking into account regional and socio-demographic characteristics. This will become the basis for a better understanding of the socio-economic burden of noncommunicable diseases and the economic damage of RFs.

Section: формирование выборкиunclassified

Section: взятие крови биобанкирование и лабораторные исследованияunclassified

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Epidemiology of Cardiovascular Diseases in Regions of Russian Federation. Third survey (ESSE-RF-3). Rationale and study design

Drapkina¹,

Shalnova²,

Imaeva³

et al. 2022

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“…-European, Middle Eastern & African Society for Biopreservation and Biobanking (ESBB) 3 ; -Европейское сообщество "Biobanking and Biomo lecular Resources Research Infrastructure -Euro pean Research Infrastructure Consortium" (BBMRI-ERIC) 4 ;…”

Section: результаты обзор международных программ обучения: история и ...mentioning

confidence: 99%

“…В соответствии с современным определением экспертов Национальной ассоциации биобанков и специалистов по биобанкированию (НАСБИО) "биобанк" (биорепозиторий, биодатабанк) является организацией или подразделением организации, которая принимает, обрабатывает, хранит и распространяет биологические образцы и ассоциированные с ними данные для текущих и будущих исследований, диагностики и терапии в соответствии со стандартными операционными процедурами и включает в себя полный комплекс мероприятий, связанных с его функционированием [2]. Единые подходы к процедурам сбора, процессинга и хранения биообразцов позволяют решать проблему воспроизводимости результатов исследований и уменьшать влияние субъективных факторов [3].…”

Section: Introductionunclassified

Training in biobanking in the context of modern medical education

Sokolova

Kamenskikh

Boguta

et al. 2022

The development of biomedical research based on predictive, preventive and personalized medicine has served as a challenge to the formation and rapid development of a novel interdisciplinary scientific area — biobanking, the main goal of which is the long-term proper storage of biological samples and related data for use in scientific and clinical research. Qualified personnel, along with the creation and development of biobank infrastructure, provide high-quality results required for biomedicine. Education and training must reflect the changing scope of knowledge and adapt to biobanking challenges. In this regard, there is an increasing need to develop and implement educational programs for staff working in and managing biobanks, as well as researchers, doctors and students who are not familiar with this area, but plan research using bioresources. The aim of this review is to present an analysis of the main biobanking directions and training programs in the world and in Russia in order to assess the existing problems and needs.

Population-nosological research biobank of the National Medical Research Center for Therapy and Preventive Medicine: analysis of biosamples, principles of collecting and storing information

Копылова¹,

Ершова²,

Pokrovskaya³

et al. 2022

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Aim. To analyze the structure of clinical data, as well as the principles of collecting and storing related data of the biobank of the National Medical Research Center for Therapy and Preventive Medicine (hereinafter Biobank).Material and methods. The analysis was carried out using the documentation available in the Biobank, as well as the databases used in its work. The paper presents clinical data on biosamples available in the Biobank as of August 18, 2021.Results. At the time of analysis, the Biobank had 373547 samples collected from 54192 patients within 37 research projects. The article presents the analysis of data representation and quantitative assessment of the presence/absence of common diagnoses in clinical projects. Approaches to documenting clinical information associated with biological samples stored in the Biobank were assessed. The methods and tools used for standardization and automation of processes used in the Biobank were substantiated.Conclusion. The Biobank of the National Medical Research Center for Therapy and Preventive Medicine is the largest research biobank in Russia, which meets all modern international requirements and is one of the key structures that improve the research quality and intensify their conduct both within the one center and in cooperation with other biobanks and scientific institutions. The collection and systematic storage of clinical abstracts of biological samples is an integral and most important part of the Biobank’s work.