Role of Bronchial Brush Cytology in Diagnosis of Central Bronchial Carcinoma

Abstract

Background : Despite the advances in imaging techniques and treatment modalities, the prognosis of lung cancer remains poor, with five-year survival of 14% at early stages and less than 5% in locally advanced stages. Before starting treatment a clear distinction between small cell and nonsmall cell carcinoma must be made, for that histopathology remains the mainstay of confirmation of diagnosis. To combat the disease successfully, it should be diagnosed at earliest possible stage. If bronchial brush cytology yield comparable diagnostic specificity, then it may easy for the patient and physician to manage this fatal disease.

Role of Bronchial Brush Cytology in Diagnosis of Bronchopulmonary Lesions

“…Sultana B et al showed squamous cell carcinoma 48.6%, adenocarcinoma 10.8 %, small cell carcinoma 08%, and no malignancy in 32.4% of cases. 21 The frequency of squamous cell carcinoma is similar to the study by Sultana B et al 21 , but it differs from other types.…”

Accuracy of Bronchial Cytological Diagnosis in Lung Lesions in Comparison with Histopathology

“…The age distribution was comparable to the studies done by Behura et al .,[ 4 ] B Sultana et al . [ 12 ], Giti et al .,[ 13 ] and Sareen et al . [ 14 ] The male-to-female ratio in this study was 2.7:1 that was comparable with the study done by Choudhury et al .…”