2023
DOI: 10.3390/jcm12175563
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Role of Cardiovascular Imaging in Risk Assessment: Recent Advances, Gaps in Evidence, and Future Directions

Francesco Perone,
Marco Bernardi,
Alban Redheuil
et al.

Abstract: Optimal risk assessment for primary prevention remains highly challenging. Recent registries have highlighted major discrepancies between guidelines and daily practice. Although guidelines have improved over time and provide updated risk scores, they still fail to identify a significant proportion of at-risk individuals, who then miss out on effective prevention measures until their initial ischemic events. Cardiovascular imaging is progressively assuming an increasingly pivotal role, playing a crucial part in… Show more

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Cited by 32 publications
(13 citation statements)
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“…Employing various imaging techniques, such as coronary computed tomography angiography, magnetic resonance imaging, and others, can enhance the identification of CVD risk, and this approach is applicable in both primary and secondary prevention strategies. The utilization of these advanced imaging methods allows for a more detailed evaluation of atherosclerotic disease, myocardial damage, and overall CV health, which can play a pivotal role in the management and prevention strategies for high-risk patients [44]. As atherosclerosis is a persistent process that affects all regions of the vasculature, it is essential to improve the assessment of parameters related to the early and accelerated progression of plaque formation, instability, and rupture.…”
Section: Discussionmentioning
confidence: 99%
“…Employing various imaging techniques, such as coronary computed tomography angiography, magnetic resonance imaging, and others, can enhance the identification of CVD risk, and this approach is applicable in both primary and secondary prevention strategies. The utilization of these advanced imaging methods allows for a more detailed evaluation of atherosclerotic disease, myocardial damage, and overall CV health, which can play a pivotal role in the management and prevention strategies for high-risk patients [44]. As atherosclerosis is a persistent process that affects all regions of the vasculature, it is essential to improve the assessment of parameters related to the early and accelerated progression of plaque formation, instability, and rupture.…”
Section: Discussionmentioning
confidence: 99%
“…Patients with non-obstructive CAD are found to be at increased risk for major cardiovascular events, including cardiovascular death and all-cause mortality [ 36 ]. Considering that these are underdiagnosed high-risk patients, future research should include the determination of an appropriate individualized cardiovascular risk assessment tool for these patients beyond existing risk scores, which would include underutilized noninvasive cardiovascular imaging techniques [ 37 ].…”
Section: Discussionmentioning
confidence: 99%
“…Blood biomarkers, such as B-type natriuretic peptide (BNP), may not consistently exhibit elevated levels in older HFpEF patients, particularly those in sinus rhythm, with obesity, and/or normal kidney function [49,50]. However, echocardiography and BNP assessment are crucial for making a guideline-directed diagnosis of HF [51,52], and additional biomarkers, such as the soluble circulating form of the suppression of tumorigenicity two receptors (sST2), may guide prognostic stratification on admission [53,54].…”
Section: Heart Failure In Older Adultsmentioning
confidence: 99%