Role of Chemiluminescence examination as non-invasive diagnostic tool in early detection of Leukoplakia

Abstract

Chemiluminescent light is a stepping stone and has the potential to revolutionize the diagnostic protocol for patients with potentially premalignant lesions. The device can be used as a general oral mucosal examination system and may in particular improve the visualization of potentially premalignant lesions.

Differential diagnosis of leukoplakia versus lichen planus of the oral mucosa based on digital texture analysis in intraoral photography

“…Methods using toluidine blue and ViziLite ® PLUS examination demonstrated a sensitivity of 100% and a specificity of 97.3%. 24 Pallagatti et al used toluidine blue to detect suspicious lesion staining in in vivo dysplastic cells. Toluidine blue is an acidophilic dye that selectively stains acidic tissue components such as DNA and RNA.…”