Role of Chitosan Hydrogels in Clinical Dentistry

Abstract

Biopolymers are organic polymers that can be treated into intricate designs with porous characteristics that mimic essential biologic components. Due to their superior biosafety, biodegradability, biocompatibility, etc., they have been utilized immensely in biomedical engineering, regeneration, and drug delivery. To obtain the greatest number of results, a literature search was undertaken in scientific search engines utilizing keywords. Chitosan is used in a variety of medical sectors, with the goal of emphasizing its applications and benefits in the clinical dental industry. Chitosan can be dissolved in liquid form and combined with other substances to create a variety of products, including fibers, hydrogels, membranes, microspheres, resins, sponges, pastes, tablets, and micro granules. Chitosan has been studied in a variety of dental applications. Chitosan is used in the prevention of caries and wear, in pulpotomy to accelerate osteogenesis in guided tissue regeneration due to its hemostatic property, and primarily to benefit from its antimicrobial activity by adding it to materials, such as glass ionomer cement, calcium hydroxide, and adhesive systems. With its antibacterial activity and biocompatibility, chitosan is leading the pack as a promising ingredient in the production of dental materials. The current review provides an update on the background, fundamentals, and wide range of uses of chitosan and its gels in dental science.

Chitosan nanoparticle applications in dentistry: a sustainable biopolymer

“…A schematic diagram summarizing the same has been given below ( Figure 7 ). ( Agrawal et al, 2023 ; Arora et al, 2023 ; Nava Juárez, 2023 ; Paradowska-Stolarz et al, 2023 ; Qu et al, 2023 ; Minervini et al, 2024 )…”

“…Drug–based chitosan scaffolds have gained lot of popularity and are extensively used for bone and periodontal healing. ( Agrawal et al, 2023 ; Arora et al, 2023 ; Nava Juárez, 2023 ).…”

Biomaterials-Based Hydrogels for Therapeutic Applications

“…Oral tissue engineering uses dental biomaterials that require a dual purpose: combating bacterial infections and promoting tissue growth. Biomaterial-based hydrogels demonstrate exceptional potential for oral tissue regeneration and drug delivery [115].…”

Silver Nanoparticles-Chitosan Nanocomposites: A Comparative Study Regarding Different Chemical Syntheses Procedures and Their Antibacterial Effect

“…Also, they have a high absorption rate; therefore, films, sponges, and hydrogels can be manufactured using chemical or green chemical syntheses. Chitosan found applications in many domains such as in treatments for obesity [ 21 ], for dentistry [ 28 ], in drug delivery for improved encapsulation [ 29 ], in soft tissue engineering as gels for regeneration of skin or epithelium reconstruction [ 30 , 31 ] and in antibacterial applications together with AgNPs [ 32 , 33 ].…”