Role of ciclosporin in steroid-responsive sudden sensorineural hearing loss

Abstract

Steroid-dependent SNHL was confirmed on audiological evaluation. Ciclosporin was administered, allowing corticosteroid therapy to be discontinued. Ciclosporin was effective at controlling all symptoms of SNHL. Remission was confirmed objectively with pure-tone audiometry.

Hearing status in patients with rheumatoid arthritis

“…However, direct exposure of the cochlea to etanercept did not induce any cochleotoxicity in an animal study 30 . Similarly, cyclosporine has not been shown to induce SNHL 31 . Therefore, ototoxicity may not explain the higher prevalence of SNHL in patients taking these medications.…”