Role of computed tomography in the staging of primary melanoma.

Buzaid, Antônio C.; Sandler, Alan; Mani, Sridhar; Curtis, Anne McB.; Poo, Wen-Jen; Bolognia, Jean L.; Ariyan, Stephan

doi:10.1200/jco.1993.11.4.638

Cited by 123 publications

(71 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our results and those of others suggest that the widespread use of CT imaging should be reserved for patients whose findings on history and physical exam are suspicious for the presence of regionally advanced or systemic disease. Buzaid et al 3 examined the role of CT scans in the initial workup of stage I, II, or III melanoma patients (including some patients with palpable lymph nodes). In their study, imaging ultimately identified true-positive findings in 2 of 151 (1.3%) patients, whereas false-positive findings for melanoma were identified in 18% of patients.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Role of radiologic imaging at the time of initial diagnosis of stage T1b‐T3b melanoma

Yancovitz

Finelt

Warycha

et al. 2007

Cancer

View full text Add to dashboard Cite

BACKGROUND. In patients with T1b‐T3b cutaneous melanoma the utility of radiologic imaging at the time of diagnosis is unclear. Whether initial imaging led to a change in stage or treatment plan was investigated. METHODS. The melanoma database was searched for patients with T1b‐T3b primary lesions, clinically N0, and asymptomatic for metastatic disease. Radiologic studies conducted before wide local excision ± sentinel lymph node biopsy as well as all further imaging and investigations were analyzed. Outcome measures included upstaging, change in initial surgical management, true‐positive, false‐positive, true‐negative, and false‐negative rates of each imaging modality. RESULTS. In all, 344 preoperative imaging studies (chest x‐ray [CXR], computed tomography [CT], positron emission tomography [PET]/CT) were performed on 158 patients, resulting in 49 findings suspicious for metastatic melanoma and 134 findings suggestive of nonmelanoma pathology. Only 1 of 344 (0.3%) studies, a PET/CT, correlated with confirmed metastatic melanoma. The false‐positive rates were CXR 5 of 7 (71.4%), chest CT 21 of 24 (87.5%), abdomen/pelvis CT 10 of 11 (90.9%), head CT 2 of 2 (100.0%), PET/CT 3 of 5 (60.0%). No patient was upstaged or had a change in initial surgical management based on preoperative imaging. The cost of all initial imaging and imaging to follow‐up abnormal findings was estimated as $555,308 for the 158 patients studied. CONCLUSIONS. Imaging at the time of initial diagnosis of T1b‐T3b, clinically N0, M0 melanoma was of low yield with a high false‐positive rate, and did not lead to upstaging or change in initial surgical management. These findings suggest that imaging of asymptomatic patients at the time of diagnosis may not be warranted. Cancer 2007. © 2007 American Cancer Society.

show abstract

Section: Discussionmentioning

confidence: 99%

“…2,3,12,14,15 Finally, the sample size of our study was limited to 158 patients, and the subgroup analyses were even more limited in size.…”

mentioning

confidence: 99%

Role of radiologic imaging at the time of initial diagnosis of stage T1b‐T3b melanoma

Yancovitz

Finelt

Warycha

et al. 2007

Cancer

View full text Add to dashboard Cite

show abstract

“…Also in treated patients, detection of recurrences or of metastases is made difficult by the wide range of potential hematogenous spread of the tumour. This requires regular chest, abdomen, pelvis and brain CT or MRI, as well as confirmatory procedures in cases of indeterminate or suspicious results [262].…”

Section: Melanomamentioning

confidence: 99%

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Rigo¹,

Paulus²,

et al. 1996

View full text Add to dashboard Cite

Abstract. Positron emission tomography (PET) is now primarily used in oncological indication owing to the successful application of fluorine-18 fluorodeoxyglucose (FDG) in an increasing number of clinical indications at different stages of diagnosis, and for staging and followup. This review first considers the biological characteristics of FDG and then discusses methodological considerations regarding its use. Clinical indications are considered, and the results achieved in respect of various organs and tumour types are reviewed in depth. The review concludes with a brief consideration of the ways in which clinical PET might be improved.

show abstract

“…In an attempt to detect these occult lesions, an initial staging evaluation is often performed on patients newly diagnosed as having melanoma. While a detailed medical history taking and physical examination are essential for this purpose, there are few data to support the use of screening studies such as chest xray films, [3][4][5][6][7] computed tomographic (CT) scans, 8,9 liver-spleen scans, [3][4][5][6][10][11][12] bone scans, [3][4][5][6]10,11 and brain scans [3][4][5][6][10][11][12] in asymptomatic patients. Despite this, the initial workup for patients with localized melanoma often includes multiple diagnostic studies, most frequently chest radiography.…”

mentioning

confidence: 99%

Use of Chest Radiography in the Initial Evaluation of Patients With Localized Melanoma

Terhune

Swanson

Johnson³

1998

Arch Dermatol

View full text Add to dashboard Cite

Role of computed tomography in the staging of primary melanoma.

Cited by 123 publications

References 8 publications

Role of radiologic imaging at the time of initial diagnosis of stage T1b‐T3b melanoma

Role of radiologic imaging at the time of initial diagnosis of stage T1b‐T3b melanoma

Oncological applications of positron emission tomography with fluorine-18 fluorodeoxyglucose

Use of Chest Radiography in the Initial Evaluation of Patients With Localized Melanoma

Contact Info

Product

Resources

About