Role of Contrast-Enhanced Ultrasound (CEUS) in Paediatric Practice: An EFSUMB Position Statement

Sidhu, Paul S.; Cantisani, Vito; Deganello, Annamaria; Dietrich, Christoph F.; Durán, Carmina; Franke, Doris; Harkányi, Z; Kosiak, Wojciech; Miele, Vittorio; Ntoulia, Aikaterini; Piskunowicz, Maciej; Sellars, Maria E.; Gilja, Odd Helge

doi:10.1055/s-0042-110394

Cited by 131 publications

(146 citation statements)

References 130 publications

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“…The use of CEUS in children, first reported in 2002, has been addressed in an EFSUMB position statement discussing the current status of CEUS and its further development in children [63]. Currently sulphur hexafluoride gas microbubbles (SonoVue™/Lumason™, Bracco SpA, Milan) has been approved in the United States by the Food and Drug Administration (FDA) as Lumason™ for characterising focal liver lesions in children ["Lumason is indicated for use with ultrasound of the liver in adult and pediatric patients to characterize focal liver lesions"] and vesico-ureteral reflux.…”

Section: Paediatric Patients and Newbornsmentioning

confidence: 99%

Untitled

2018

Ultrasound Int Open

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Section: Paediatric Patients and Newbornsmentioning

confidence: 99%

Untitled

2018

Ultrasound Int Open

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“…Comments on EFSUMB guidelines have been published as well [18,32,33,[36][37][38][39][40][41][42][43]. Most recently we refer to the Pediatric Position paper on the use of CEUS [44].…”

Section: Historymentioning

confidence: 99%

“…Update CEUS non-liver Previous contrast enhanced ultrasound (CEUS) documents from the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB) have been published encompassing hepatic and non-hepatic applications with a statement on CEUS use in paediatric applications [44]. The CEUS non-liver update reflects the current applications in non-hepatic CEUS and updates the previous EFSUMB guidelines published in 2012 [13].…”

Section: Update Elastography Liver Guidelinesmentioning

confidence: 99%

The EFSUMB website, a great source for ultrasound information and education

Dietrich

Rudd²,

Saftiou

et al. 2017

Med Ultrason

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The aim of this updated EFSUMB-website guide is to introduce readers to EFSUMB’s wide ranging activities. The most recent are the guidelines on interventional ultrasound and intestinal ultrasound and updated CEUS Non-Liver and Elastography Liver Guidelines which can be freely downloaded. Hosting eBooks on our website is another new departure, most importantly the EFSUMB Course Book on Ultrasound available in a second edition as an eReader and an online Student Edition of the ECB. EFSUMB has been active with updating Guidelines; those mentioned above have all been revised or written in thelast two years. Webinars have been introduced and participation is possible online but can be reviewed later along with recent recordings of Euroson Schools. The EFSUMB Newsletter in the EJU promotes our activities and topical articles intended to reach all our members with the online version hosted on our website. The Case of the Month continues to be one of EFSUMB’s most visited sites and in the last few years has been translated into 14 different languages including Chinese. In conclusion, this article aims to provide an updated guide to the website educational sites of the European Federation of Societies for Ultrasound in Medicine and Biology (EFSUMB).

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“…use of ultrasonography contrast agents is still "off-label" for the paediatric population in Europe, it has been widely used with documented safety and accuracy. 1,9,10 A recent and important development has been the approval by the Food and Drug Administration of the use of CEUS for liver examination in children in the USA, 11 and this will alter application not only in the USA but also across the world. Ultrasound practitioners should be mindful that many drugs are used "off-label" in children, and this is not prohibited by medical regulatory authorities.…”

Section: Introductionmentioning

confidence: 99%

Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

Rafailidis¹,

Deganello²,

Watson³

et al. 2017

BJR

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Contrast-enhanced ultrasound (CEUS) represents a complementary technique to greyscale and colour Doppler ultrasonography which allows for real-time visualization and characterization of tissue perfusion. Its inherent advantages in the child makes ultrasonography an ideal imaging modality; repeatability and good tolerance along with the avoidance of CT, a source of ionizing radiation, renders ultrasonography imaging desirable. Although currently paediatric CEUS is principally used in an "off-label" manner, ultrasonography contrast agents have received regulatory approval for assessment of paediatric focal liver lesions (FLL) in the USA. The safety of ultrasound contrast-agents is well documented in adults, as safe as or even surpassing the safety profile of CT and MR contrast agents. Except for the established intracavitary use of CEUS in voiding urosonography, i.v. paediatric applications have been introduced with promising results in the abdominal trauma initial diagnosis and follow-up, characterization and differential diagnosis of FLL and characterization of lung, pleura, renal and splenic pathology. CEUS has also been used to detect complications after paediatric transplantation, evaluate inflammatory bowel disease activity and assess tumour response to antiangiogenic therapy. The purpose of this review was to present these novel i.v. paediatric applications of CEUS and discuss their value.

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Role of Contrast-Enhanced Ultrasound (CEUS) in Paediatric Practice: An EFSUMB Position Statement

Cited by 131 publications

References 130 publications

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Untitled

The EFSUMB website, a great source for ultrasound information and education

Enhancing the role of paediatric ultrasound with microbubbles: a review of intravenous applications

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