Role of Corneal Collagen Cross-Linking in Pseudophakic Bullous Keratopathy

Arora, Ritu; Manudhane, Aditi; Saran, Ravindra Kumar; Goyal, Jawahar Lal; Goyal, Gaurav; Gupta, Deepa

doi:10.1016/j.ophtha.2013.07.038

Cited by 38 publications

(31 citation statements)

References 31 publications

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“…Although the pain scoring scale used likely lacked sensitivity for detecting more subtle signs of ocular discomfort, these results are similar to the first canine‐reported cases of CXL‐treated BK described by Pot et al . and are consistent with literature describing CXL‐treated BK in humans . We observed that CXL treatment reduced corneal edema for the first 3 months, but the edema returned to near‐pre‐operative values at 6 months.…”

Section: Discussionsupporting

confidence: 89%

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Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Famose

2015

Veterinary Ophthalmology

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Section: Discussionsupporting

confidence: 89%

“…CXL is gaining popularity in human ophthalmology as a modality for the palliative treatment of (particularly pseudophakic) BK. CXL has been used to provide temporary symptomatic relief and to improve vision in human patients with BK of various origins . CXL has recently been described for the treatment of BK in two dogs .…”

Section: Introductionmentioning

confidence: 99%

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Famose

2015

Veterinary Ophthalmology

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“…There was significant improvement in visual acuity, corneal thickness, pain score and corneal haze following CXL at 1 month postoperatively. However, all parameters had worsened by the 3-month postoperative examination [178]. …”

Section: Other Indications For Riboflavin-uvx Collagen CXLmentioning

confidence: 99%

Corneal Collagen Crosslinking: A Systematic Review

Sorkin

Varssano²

2014

Ophthalmologica

166

122

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Keratoconus (KCN) is an ectatic disorder with progressive corneal thinning and a clinical picture of corneal protrusion, progressive irregular astigmatism, corneal fibrosis and visual deterioration. Other ectatic corneal disorders include: post-LASIK ectasia (PLE) and pellucid marginal degeneration (PMD). Corneal crosslinking (CXL) is a procedure whereby riboflavin sensitization with ultraviolet A radiation induces stromal crosslinks. This alters corneal biomechanics, causing an increase in corneal stiffness. In recent years, CXL has been an established treatment for the arrest of KCN, PLE and PMD progression. CXL has also been shown to be effective in the treatment of corneal infections, chemical burns, bullous keratopathy and other forms of corneal edema. This is a current review of CXL - its biomechanical principles, the evolution of CXL protocols in the past, present and future, indications for treatment, treatment efficacy and safety.

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“…In humans it has been investigated the use of collagen cross-linking for the treatment of BK and good results have been obtained depending on the severity of the lesion (Arora et al 2013). However, recent studies in dogs and cats suggests that new studies should be conducted to validate this technique (Pot et al 2015, Spiess et al 2014.…”

Section: Discussionmentioning

confidence: 99%

Bullous keratopathy in a yellow-headed caracara (Milvago chimachima) treated with a modified third eyelid flap

et al. 2016

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A Yellow-headed Caracara (Milvago chimachima) was submitted to the Ophthalmology Service of the Federal University of Bahia with a corneal abnormality. During ophthalmic evaluation the right cornea was stained positively with fluorescein; a blurred bullous lesion, with irregular surface, compatible with the diagnosis of bullous keratopathy was found. This is a rare condition in a bird which was treated successfully with a modified third eyelid flap associated with antibiotic and hyaluronic acid eye drops. The adopted therapeutic proved to be simple to implement and viable for repair of the bullous keratopathy in the Yellow-headed caracara.

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Role of Corneal Collagen Cross-Linking in Pseudophakic Bullous Keratopathy

Cited by 38 publications

References 31 publications

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Evaluation of accelerated corneal collagen cross‐linking for the treatment of bullous keratopathy in eight dogs (10 eyes)

Corneal Collagen Crosslinking: A Systematic Review

Bullous keratopathy in a yellow-headed caracara (Milvago chimachima) treated with a modified third eyelid flap

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