Role of Culinary Indian Spices in the Regulation of TGF‐β Signaling Pathway in Inflammation‐Induced Liver Cancer
Ajay Sarija Asoka,
Anusha Kolikkandy,
Bhagyalakshmi Nair
et al.
Abstract:ScopeHepatocellular carcinoma (HCC) results from various etiologies, such as Hepatitis B and C, Alcoholic and Non‐alcoholic fatty liver disorders, fibrosis, and cirrhosis. About 80 to 90% of HCC cases possess cirrhosis, which is brought on by persistent liver inflammation. TGF‐β is a multifunctional polypeptide molecule that acts as a pro‐fibrogenic marker, inflammatory cytokine, immunosuppressive agent, and pro‐carcinogenic growth factor during the progression of HCC. The preclinical and clinical evidence ill… Show more
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