“…Enrichment of maturation media with cumulus cells (Al Zeidi et al, 2022), growth factors and hormones (Bunel et al, 2020;Ko et al, 2021;Kumar et al, 2020;Wolff et al, 2022), and other factors (Martínez-Quezada et al, 2021;Zabihi et al, 2021;Saini et al, 2022;Chelenga et al, 2022) improves oocyte maturation and embryo development thereafter (Gordon 2003;Baruffi et al, 2004;Somfai et al, 2012). In addition, super-stimulation of ovarian follicles via gonadotropin injections resulted in changes in small, medium, and large follicles according to the number and dose of gonadotropin injections and side of the ovary (Abdelnaby et al, 2021).…”