Role of delayed cord clamping in prevention of necrotizing enterocolitis in preterm neonates: a systematic review

Abstract

The role of DCC in the prevention of NEC is supported by the current evidences. However, given the small sample sizes and other limitations of these studies, current evidences are not sufficient. We need large high-quality trials, with sufficient power to reliably assess clinically relevant differences in important outcomes.

Effect of oropharyngeal colostrum therapy in the prevention of necrotising enterocolitis among very low birthweight neonates: A meta‐analysis of randomised controlled trials

“…Mortality with surgical intervention is as high as 50% and increases further up to 100% in extremely low birthweight (ELBW) neonates . Antenatal steroids , delayed cord clamping , standardised feeding protocol, probiotics and bovine lactoferrin comprise the varied strategies for the prevention of NEC in preterm neonates.…”

Directive clinique no 424 : Prise en charge du cordon ombilical chez le nourrisson prématuré ou à terme

“…De plus, il a été démontré que le CRC diminue de façon significative les risques de morbidité, y compris le risque d'hémorragie intraventriculaire (HIV) (RR : 0,83; IC à 95 % : 0,70-0,99) 1 et d'entérocolite nécrosante (ECN) (RR : 0,59; IC à 95 % : 0,37-0,94) 11 . Les valeurs de pression artérielle moyenne 1 et d'hématocrite 5 étaient significativement plus élevées dans le groupe de CRC comparativement au groupe de CIC.…”

Turkish Neonatal Society Necrotizing Enterocolitis Diagnosis, Treatment and Prevention Guidelines

“…A low grade of evidence has shown decreased incidence of NEC in preterms who have been exposed to delayed cord clamping or cord milking, however, these interventions should be based according to the NRP guidelines. 32 , 33 …”