Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part I. Serum unsaturated fatty acids

Adult male albino rats were supplemented with edible plant oils, corn maize and cotton seed oils and their semihydrogenated forms (Heliopolis and Sultan cooking fat). In general, the supplementation of tested oils produced increasing effect on the levels of total unsaturated fatty acids (UFA), C18:1, C18:2 and C20:4 UFA of liver and heart of rats. Liver content of UFA showed very highly significant increases in the levels of C18:1 and C18:2 in all groups of rats fed with tested oils accompanied with non significant changes in total UFA and C20:4 levels. Heart content of UFA showed increases in the levels of C18:1 and C18:2 and insignificant changes observed in total UFA and C20:4, except, in rats fed with sultan cooking fat, showed a significant increase in the level of total UFA. The level of increase in C18:1 and C18:2 was very highly significant in case of rats fed corn maize oil and Sultan cooking fat, and significant in case of rats fed cotton seed oil and Heliopolis cooking fat. Also, liver and heart UFA contents were significantly increased after antioxidant (Butylated hydroxy anisol, BHA) administration. Addition of BHA to tested diets abolished or minimized fatty infiltration produced by dietary fatty diet in the liver cells.

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Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part II. Liver and heart unsaturated fatty acids

Abu‐El‐Zahab

Aida

El-Sisi

1993

Nahrung

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Fatty Acid Composition of Serum, Adipose Tissue, and Liver in Rats Fed Diets Containing Corn Oil or Cottonseed Oil

Radcliffe

Czajka-Narins

Imrhan

2004

Plant Foods Hum Nutr

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There have been few studies on the effect of cottonseed oil (CSO), one of the most commonly used vegetable oils in the United States, on indices of lipid status either in the rat or in any other species. Previous studies with rats have focused on the effect of CSO, versus that of other vegetable oils, on the concentration of cholesterol in serum and liver or on a limited number of fatty acids in serum, adipose tissue, or liver. The present study was designed to compare more fully than in previous studies the effect of CSO to that of corn oil (CO) on the fatty acid composition of serum, adipose tissue, and liver. Two groups of male rats (n = 10 each) were used, each fed one of two purified diets containing 100 g/kg of either CO or CSO. Between-group differences included higher values (mol% total fatty acids) in adipose tissue for palmitic acid and stearic acid, but lower values in serum, adipose tissue, and liver for cis-vaccenic acid and oleic acid (C18:1n-9) for the CSO group than the CO. In addition, values in serum, adipose tissue, and liver for alpha-linolenic acid (C18:3n-3) and its metabolite, docosahexaenoic acid (C22:6n-3), were lower for the CSO group than the CO. There was no effect of diet on serum or tissue levels of n-6 fatty acids (linoleic acid, dihomo-y-linolenic acid, and arachidonic acid). Differences in fatty acid compositions noted, e.g., those for C18:ln-9 and C22:6n-3, mainly reflected compositional differences between the two oils. Thus, use of CSO rather than CO affected serum and tissue concentrations of saturated, monounsaturated, and n-3 polyunsaturated fatty acids (PUFAs) but had no effect on n-6 PUFA status.

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Lipids and Tocopherols in Serum and Liver of Female Rats Fed Diets Containing Corn Oil or Cottonseed Oil

Radcliffe

Czajka-Narins

2006

Plant Foods Hum Nutr

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Growing female rats were fed diets containing either corn oil (CO) or cottonseed oil (CSO) to determine if the previously reported lowering effect of CSO versus CO on serum total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) was sex specific and to compare the effect of these two oils on serum and tissue concentrations of RRR-alpha-tocopherol (alpha-T) and RRR-gamma-tocopherol (gamma-T), the two major tocopherols in these oils. In a 4-week study, groups of rats (n = 10 each) were fed diets containing 100 g/kg of either CO or CSO. TC was lower for group CSO than group CO. Serum concentrations of HDL-C, non-HDL-C, triglycerides (TGs), as well as the TC/ HDL-C ratio and the hepatic concentrations of cholesterol and TGs, were unaffected by diet. For serum and liver, between-group differences were noted for the concentrations of alpha-T (where values were higher for group CSO) and gamma-T (where values were lower for group CSO). These differences reflected differences between the oils in their concentrations of these tocopherols. Thus, CSO has a lowering effect on TC for both sexes, but on HDL-C for male animals only; replacement of CO with CSO results in changes in tocopherol status.

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Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part I. Serum unsaturated fatty acids

Cited by 3 publications

References 22 publications

Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part II. Liver and heart unsaturated fatty acids

Role of dietary lipids and butylated hydroxy anisol (BHA) administration on albino rats. Part II. Liver and heart unsaturated fatty acids

Fatty Acid Composition of Serum, Adipose Tissue, and Liver in Rats Fed Diets Containing Corn Oil or Cottonseed Oil

Lipids and Tocopherols in Serum and Liver of Female Rats Fed Diets Containing Corn Oil or Cottonseed Oil

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