2016
DOI: 10.5152/dir.2016.15167
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Role of diffusion-weighted imaging for detecting bone marrow infiltration in skull in children with acute lymphoblastic leukemia

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Cited by 23 publications
(10 citation statements)
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References 26 publications
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“… 3,4 However, DWI is most often referred for intracranial pathologies. 5 Usage of DWI in the extracranial sites such as abdomen and pelvis is also encouraging and has become a routine sequence in oncologic settings. 6 This feature can be made use of in differentiating benign and malignant lesions and assessing treatment.…”
Section: Discussionmentioning
confidence: 99%
“… 3,4 However, DWI is most often referred for intracranial pathologies. 5 Usage of DWI in the extracranial sites such as abdomen and pelvis is also encouraging and has become a routine sequence in oncologic settings. 6 This feature can be made use of in differentiating benign and malignant lesions and assessing treatment.…”
Section: Discussionmentioning
confidence: 99%
“…Nishi et al were the first to describe the successful application of DWI to predict bone marrow infiltration in pediatric patients with different leukemia subtypes, using the clivus‐to‐pons signal intensity ratios . Cao et al reported the successful use of DWI to capture treatment response in pediatric ALL patients, based on normalization of ADC values measured in the skull . Finally, Niu et al investigated the predictive value of pretherapeutic intravoxel‐incoherent motion (IVIM) MRI—a variation of DWI that enables the assessment of the perfusion component in addition to true molecular diffusion—in patients with AML.…”
Section: Leukemiamentioning
confidence: 99%
“…Ein leukämisches Infiltrat weist in MRT-Aufnahmen eine T1w Hypointensität und eine variable T2w Signalintensität mit leichter Kontrastmittelanreicherung auf [28,29]. Eine Diffusionsrestriktion kann vorliegen und stellt ein hilfreiches Bildgebungsmerkmal für die Beurteilung des therapeutischen Ansprechens dar [31]. In CT-Aufnahmen ohne Kontrastmittelgabe erscheinen granulozytäre Sarkome iso-oder hyperdens zur Muskulatur.…”
Section: Merkeunclassified