Role of Duplex Ultrasound in Diagnosis of Prostate Cancer and Localization for Biopsy

Abstract

Background: Prostate cancer is a common malignancy among men and is one of major problem of health care system. Ultrasonography is useful, safe, and available method for evaluation of prostate problem. The aim of present study was to evaluate the role of duplex ultrasound in diagnosis of prostate cancer and localization for biopsy. Methods & Materials: In a descriptive analytical study, 27 patients with increased level of PSA, who were referred to ultrasonography ward of Imam Reza Hospital for prostate biopsy, were included in the study and examined with color doppler and duplex ultrasonography. Biopsy was done for all patients using transrectal guided ultrasonography. Resistance index (RI), pulsatility index (PI), prostate volume, and pathology findings of biopsy, were evaluated. Results: Among 27 patients, 12 patients (44.4%) had prostate cancer and 15 patients (55.6%) had benign prostatic hyperplasia (BPH). In evaluation of RI & PI in prostate arteries, there were no significant differences between patients with malignancy and patients with BPH (P>0.05). Mean volume of prostate in patient with prostate cancer was 36.56±3.13 ml and in patients with BPH was 54.76±5.42 ml. Mean volume of prostate in patients with BPH was significantly more than patients with prostate cancer (P=0.020). Conclusion: Based on the findings of present study; there is no significant correlation between vascular features of prostate arteries and prostate malignancy, and volume of prostate in patients with BPH was significantly higher than patients with prostate cancer.