Role of Fibrin Glue in Management of Perianal Fistula in Assiut University Hospital

Abstract

Background: A fistula-in-ano is an abnormal hollow tract or cavity that is lined with granulation tissue and that connects a primary opening inside the anal canal to a secondary opening in the perianal skin; secondary tracts may be multiple and can extend from the same primary opening. Patients and Methods:In our study we had 40 patients who were complainingof fistula in ano (high and low perianal fistula). They were evaluated in the post-operative period for the complications as recurence, sphincteric disturbance, postoperative abscess and post-operative pain from Results: After injection of 40 cases of perianal fistula it was found that 5 cases out of 16 cases of high perianal fistula (31.2%) developed recurrence of their fistulas tract, while 11cases did not develop recurrence (69.8%) after 6 moths follow-up. On the other hand 5 cases of low perianal fistula out of 24 cases (20.8%) developed recurrence of their fistulas with 19 cases (79.2%) that did not develop recurrence their fistulous tract after 6 months follow-up. Other complication noticed in this study was post-operative abscess and reported in 3 cases only (7.5%). There was no post-operative incontinence or post-operative pain or bleeding reported in this study.Conclusion: Injection of fibrin glue in aperianal fistula is simple, easy and safe technique with lower rate of complication as loss of sphincteric function, post-operative pain, intra operative bleeding and post-operative wound infection. This technique can be repeated even at the out patient clinic.