Role of Glycemic Control on Ischemic Stroke in Af

Yenigalla, Sowjanya; Kudron, E.; Mehdi, Noor-ul-huda A.; Kaur, Navneet; Ghobrial, Ibrahim; Tuft, Marie; Kiazand, Mehrshid

doi:10.1016/j.chest.2019.08.424

Cited by 2 publications

(1 citation statement)

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“…Of note, some recent studies did not yield increased risk of stroke in AF patients with poor or intermediate glycemic control [ 20 , 21 , 67 , 72 , 73 ]. A potential reason proposed to account for that discordance might be the underlying mechanism for stroke in patients with AF, which is mainly atrio-embolic and not so often due to underlying atherosclerosis [ 67 , 74 , 75 ].…”

Section: Relevance Of Glycated Hemoglobin Measurement In Afmentioning

confidence: 99%

Glycemic control and atrial fibrillation: an intricate relationship, yet under investigation

Papazoglou

Κάρτας

Moysidis

et al. 2022

Cardiovasc Diabetol

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Atrial fibrillation (AF) and diabetes mellitus (DM) constitute two major closely inter-related chronic cardiovascular disorders whose concurrent prevalence rates are steadily increasing. Although, the pathogenic mechanisms behind the AF and DM comorbidity are still vague, it is now clear that DM precipitates AF occurrence. DM also affects the clinical course of established AF; it is associated with significant increase in the incidence of stroke, AF recurrence, and cardiovascular mortality. The impact of DM on AF management and prognosis has been adequately investigated. However, evidence on the relative impact of glycemic control using glycated hemoglobin levels is scarce. This review assesses up-to-date literature on the association between DM and AF. It also highlights the usefulness of glycated hemoglobin measurement for the prediction of AF and AF-related adverse events. Additionally, this review evaluates current anti-hyperglycemic treatment in the context of AF, and discusses AF-related decision-making in comorbid DM. Finally, it quotes significant remaining questions and sets some future strategies with the potential to effectively deal with this prevalent comorbidity.

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