Role Of Habitual Risk Factors On Oral Squamous Cell Carcinoma

Abstract

Squamous cell carcinoma is the most common oral malignancy. Betel quid, betel quid with tobacco, smoking, alcohol consumption, mechanical irritation, genetic are the most important risk factors for Oral Squamous Cell Carcinoma (OSCC). The aim of the study was to determine the role of habitual risk factors inOral Squamous Cell Carcinoma. Materials and Methods: This is a cross-sectional study for the determination of the risk factors of OSCC over 2 years period of January 2011 to December 2012. Department of Oral & Maxillofacial Surgery, Bangabandhu Sheikh Mujib Medical University, Dhaka, Department of Oral & Maxillofacial Surgery, Dhaka Dental College Hospital, Dhaka,National Institute of Cancer Research & Hospital (NICRH), Mohakhali, Dhaka and Health and Hope Hospital, Dhaka from January 2011 to December 2012 Results:250 patients, comprising 44% male and 56% female were included in the study. Overall mean age was 55.94±10.93 years. The patients of OSCChavemost common habit of betel quid with tobacco 124(49.6%), then betel quid with tobacco and smoking 49(19.6%), betel quid with tobacco and Gul 19(7.6%), only smoking 13(5.2%), Betel quid without tobacco and smoking 13(5.2%), betel quid without tobacco 12(5.2%), betel quid with tobacco and catechu (Khoir) 4(1.6%), betel quid with tobac- co, smoking and gul 3(1.2%), betel quid without tobacco,smoking and alcohol 2(0.8%), betel quid without tobacco and gul 2(0.8%), betel quid without tobacco, smoking and gul 1(0.4%), betel nut chewing 1(0.4%), mechanical irritation but no habit 5(2.0%) and no habitual history 2(0.8%). Conclusion: According to this study betel quid, betel quid with tobacco, gul, smoking are the important risk factors in OSCC.Update Dent. Coll. j: 2018; 8 (1): 29-35

Immunohistochemical Expression of Epidermal Growth Factor Receptor (EGFR) in Oral Squamous Cell Carcinoma and Oral Potentially Malignant Disorders

“…In our study, the male-to-female ratio of OSCC was 2.16:1. Our results are similar to studies by Khalid et al 24 and Siriwardena et al 25 Contrary to our study Hannan et al 26 reported a slightly higher frequency of OSCC in females (M: F=1:1.27) in Dhaka, Bangladesh. The common site involved by OSCC in our study was buccal mucosa (34.2%).…”

Rural profile of oral squamous cell carcinoma (OSCC) survival patients attending in tertiary level hospital in Bogura: a hospital based retrospective observational study.

“…To implement this objective a retrospective observational study was performed in TMSS Rafatullah Community Hospital and Shaheed Ziaur Rahman Medical College Hospital (ShSMCH) two tertiary level hospital in Bogura with study period six months (May 2019 to October 2019). Inclusion criteria was whom have hispathologically positive case history of oral squamous cell carcinoma [4] . At the same time, we excluded patients who are contraindicated for chemotherapy as well as other severe co-morbid diseases.…”

“…All patients reported in Oral and Maxillofacial Surgery Department and Oncology Department were included as sample of analysis. Data of all histopathologically proven OSCC cases about their both socio demographic and clinical contour was collected through face to face interview by a pretested semi-structured open-ended questionnaire methods [4,5,11] . All collected data was analyzed by IBM SPSS version 22, interpreted by descriptive statistics and to describe correlation between the variable chi-square test and p-value was analyzed [4] .…”