Role of hormones in hypoactive sexual desire disorder and current treatment

Abstract

Over the decades, female sexual dysfunction (FSD) has grown to be an increasingly potential problem that complicates the quality of life among women. In the current review, FSD refers to recurrent and persistent problems with sexual orgasm, desire, or response. One of the most common subtypes of FSD that has evoked increased research interest in the scientific community is hyposexuality. Today, there is a consensus that hyposexuality is a multifactorial condition that manifests with reduced sexual desire resulting in significant interpersonal distress. The objective of the current review was to examine how hormonal profile triggers propagate hypoactive sexual desire disorder (HSDD), and to highlight effective treatment interventions that can be used to manage the condition. The current review describes HSDD as a sexual dysfunction characterized by the absence or lack of sexual desire and fantasies for sexual activities. The review argues that even if the role of sexual hormones is essential in modulating HSDD through therapeutic interventions, an effective comprehension of the biologic mechanisms underlying HSDD is necessary. There is a consensus in the literature that HSDD still poses significant challenges due to the lack of properly formulated treatment regimens and absence of clear clinical guidelines. That is, a better intervention consisting of both psycho-relational and biologic aspects is compulsory if tailored management and accurate diagnosis of HSDD in clinical practice are to be realised. The review concludes that, to date, a reliable clinical intervention to manage hyposexuality is still absent and more interventions, in terms of safety and efficacy, are required. Thus, additional investigation is required to document precise hormonal or non-hormonal pharmacotherapeutic agents for individualised care among patients with HSDD.

Perceptions of Chinese Patients Treated for Gynaecological Cancer about Sexual Health and Sexual Information Provided by Healthcare Professionals: A Qualitative Study

“…A loss of sexual interest may be caused by a dramatic decrease in oestrogen levels due to curative cancer treatment [ 31 ], which has been shown to be associated with the occurrence of vaginal dryness and dyspareunia. These symptoms reduced the patients’ desire for sexual activities and decreased the frequency of sexual activity with their partners [ 32 ], as reported by some participants of our study. Furthermore, the patients in our study reported a poorer body image, consistent with the findings of a previous study [ 13 ], and a sense of being an imperfect woman.…”

Exploring Conflict, War and HIV/AIDS on Health of the Internally Displaced Persons living in North Central Nigeria

“…Technically, the young uniform services personnel posted for peacekeeping are young, energetic trained risk-taking o cers within their early 20s and 30s, the most vulnerable group to HIV infection. Also, biologically younger o cers in their early 20s and 30s experienced high secretion of sex hormones (testosterone and progesterone), making them sensitive to sexual desire (Agaba et al, 2016;AlAwlaqi, Amor, & Hammadeh, 2017). Coincidently, this same age group posted outside their homes and immediate families for a very long period represents the most vulnerable age affected by HIV/AIDS (CDC, 2018a;CDC, 2018b;UNAIDS, 2015).…”

Bakteriyel vajinoz ve tedavisinin cinsel fonksiyonlar üzerine etkileri: Bir kesitsel anket çalışması

“…A portion of patients think that their condition is a part of their normal lives, and discharge is physiologic, because discharge is not always vexing. Sometimes discharge is seen only in small amounts that only smudges on the vaginal walls and labia, it can be in excessive amounts that will lead the patient to make a visit for examination and to accumulate in the posterior fornix [3].…”

“…While the most frequent complaints at presentation are vaginal discharge and bad odor that irritate the couple during sexual intercourse, complaints about the sense of disgust and lack of pleasure from the intercourse are mentioned more when the anamnesis is deepened somehow. This in turn affects the sexual lives of patients and can result in sexual dysfunction in patients [3].…”