2021
DOI: 10.6000/1927-7229.2017.06.04.3
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Role of Hormones in Oral Squamous Cell Carcinoma - An Update

Abstract: Background: Hormones have been recognized as regulator of the cell growth, differentiation and maturation. It has become increasingly evident that hormone may play a crucial role in the genesis and progression of several cancers like those of breast, ovary, testis, thyroid, prostrate including oral cancer. Aim: Present overview aims to discuss and provide data on possible role of various hormones including stress hormone, sex hormone, parathyroid and related hormone protein, melatonin and active metaboli… Show more

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Cited by 2 publications
(1 citation statement)
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“…Since the first reports of CIC findings were made over 100 years ago [17,62,63], they have become common findings in malignancies such as lung cancer [64], breast cancer [11,65], and oral cancer [12,66], and have been linked to an increase in tumor aggressiveness [67,68], resistance [22] and survival [69][70][71], leading to worse prognosis [25,72]. However, despite being easily identifiable in routine H/E stains and electron microscopy [69,[73][74][75][76], there is a need for models that enable further study of these events in vitro.…”
Section: Discussionmentioning
confidence: 99%
“…Since the first reports of CIC findings were made over 100 years ago [17,62,63], they have become common findings in malignancies such as lung cancer [64], breast cancer [11,65], and oral cancer [12,66], and have been linked to an increase in tumor aggressiveness [67,68], resistance [22] and survival [69][70][71], leading to worse prognosis [25,72]. However, despite being easily identifiable in routine H/E stains and electron microscopy [69,[73][74][75][76], there is a need for models that enable further study of these events in vitro.…”
Section: Discussionmentioning
confidence: 99%