Role of Human Chorionic Gonadotropin in Patients with Pure Seminoma

Rüther, U.; Rothe, B.; Grunert, Kirsten; Bader, Hermann; Sessler, Roland; Nunnensiek, C.; Rassweiler, Jens; Lüthgens, M.; Eisenberger, F.; Jipp, Peter

doi:10.1159/000475361

Cited by 23 publications

(8 citation statements)

References 11 publications

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“…It has the same clinical and evolutive characteristics as the non-secreting seminoma. Its treatment is controversial but two studies have been able to determine that its prognosis is identical to that of the non-secreting form [94,95]. In stage I, the concentration of this glycoprotein should return to normal after surgery [95].…”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…Its treatment is controversial but two studies have been able to determine that its prognosis is identical to that of the non-secreting form [94,95]. In stage I, the concentration of this glycoprotein should return to normal after surgery [95]. If not, it is strongly suggestive of disease of at least stage II [94].…”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…If not, it is strongly suggestive of disease of at least stage II [94]. In this case, the blood level of βHCG should be normalized after an adjuvant RT or CHT treatment [95]. …”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…This was probably due to a selection bias. Even if a βHCG level is associated with a more important tumor volume, recent series report a prognosis comparable to the non-secreting forms [94,95,97,98]. The experience in stage II secreting seminomas is more limited.…”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…The treatment is also generally the same as that for non-secreting seminomas. The prognosis is independent of the βHCG blood level [92,94,95,99]. …”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

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Pure seminoma: A review and update

et al. 2011

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Pure seminoma is a rare pathology of the young adult, often discovered in the early stages. Its prognosis is generally excellent and many therapeutic options are available, especially in stage I tumors. High cure rates can be achieved in several ways: standard treatment with radiotherapy is challenged by surveillance and chemotherapy. Toxicity issues and the patients' preferences should be considered when management decisions are made. This paper describes firstly the management of primary seminoma and its nodal involvement and, secondly, the various therapeutic options according to stage.

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Section: βHcg Secreting Seminomamentioning

confidence: 99%

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…If not, it is strongly suggestive of disease of at least stage II [94]. In this case, the blood level of βHCG should be normalized after an adjuvant RT or CHT treatment [95]. …”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

Section: βHcg Secreting Seminomamentioning

confidence: 99%

“…The treatment is also generally the same as that for non-secreting seminomas. The prognosis is independent of the βHCG blood level [92,94,95,99]. …”

Section: βHcg Secreting Seminomamentioning

confidence: 99%

See 3 more Smart Citations