Role of MTHFR, IRF6, PAX7 and TP63 SNPs in susceptibility to non‐syndromic orofacial cleft, a candidate gene study in a Portuguese population
João Mendes,
Adriana Rocha Guimarães,
Joana Martins Ribeiro
et al.
Abstract:BackgroundNon‐syndromic orofacial cleft (NSOC) is a complex phenotype, involving multiple genetic and environmental factors. Association studies exploring the genetic susceptibility to this prevalent oral malformation show variability of results in different populations. Using a candidate gene approach, we aimed to verify the role of four single‐nucleotide polymorphisms (SNPs) in the susceptibility to NSOC in Portuguese patients.MethodsA total of 254 non‐consanguineous individuals of Portuguese were recruited,… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.