Role of imaging for patients with colorectal hepatic metastases: what the radiologist needs to know

Reiter, Michael J.; Hannemann, Nathan P.; Schwope, Ryan B.; Lisanti, Christopher J.; Learn, Peter A.

doi:10.1007/s00261-015-0507-8

Cited by 9 publications

(4 citation statements)

References 64 publications

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“…Imaging techniques include computed tomography (CT), magnetic resonance (MR), positron emission tomography (PET) and ultrasound. The best methods for CRClm detection are CT and MR [7]. CT with a multiphasic technique and optimal scanning parameters providing high contrast and spatial resolution should be the initial imaging tests.…”

Section: Colorectal Liver Metastases Detectionmentioning

confidence: 99%

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

et al. 2019

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Colorectal cancer (CRC) has the second-highest tumor incidence and is a leading cause of death by cancer. Nearly 20% of patients with CRC will have metastases at the time of diagnosis, and more than 50% of patients with CRC develop metastatic disease during the course of their disease. A group of experts from Medicine and Molecular Imaging met to discuss and provide a multidisciplinary consensus on the management of liver metastases in patients with CRC. The group defined the different scenarios in which the disease can present: fit or unfit patients with resectable liver metastases, patients with potential resectable liver metastases, and patients with unresectable liver metastases. Within each scenario, the different strategies and therapeutic approaches are discussed.

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Section: Colorectal Liver Metastases Detectionmentioning

confidence: 99%

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

et al. 2019

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“…Further, these targeted therapies are non-systemic, often only addressing one or few lesions, and are not expected to prevent the development of additional tumours, thus potentially having inconsistencies with traditional response assessment criteria. 26,[39][40][41] This has led to the development of tumour viability-based criteria for specific cancers tailored to specific therapies, such as modified RECIST (mRECIST). Other viability-based criteria include the European Association for the Study of Liver (EASL) guidelines and Response Evaluation Criteria in Cancer of the Liver for hepatocellular carcinoma (HCC), Morphology, Attenuation, Size, and Structure criteria and Size and Attenuation CT criteria for RCC, and the Choi Criteria for gastrointestinal stromal tumour.…”

Section: Response To Therapymentioning

confidence: 99%

Volumetric analysis at abdominal CT: oncologic and non-oncologic applications

Planz¹,

Lubner²,

Pickhardt

2019

BJR

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Volumetric analysis is an objective three-dimensional assessment of a lesion or organ that may more accurately depict the burden of complex objects compared to traditional linear size measurement. Small changes in linear size are amplified by corresponding changes in volume, which could have significant clinical implications. Though early methods of calculating volumes were time-consuming and laborious, multiple software platforms are now available with varying degrees of user-software interaction ranging from manual to fully automated. For the assessment of primary malignancy and metastatic disease, volumetric measurements have shown utility in the evaluation of disease burden prior to and following therapy in a variety of cancers. Additionally, volume can be useful in treatment planning prior to resection or locoregional therapies, particularly for hepatic tumours. The utility of CT volumetry in a wide spectrum of non-oncologic pathology has also been described. While clear advantages exist in certain applications, some data have shown that volume is not always the superior method of size assessment and the associated labor intensity may not be worthwhile. Further, lack of uniformity among software platforms is a challenge to widespread implementation. This review will discuss CT volumetry and its potential oncologic and non-oncologic applications in abdominal imaging, as well as advantages and limitations to this quantitative technique.

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“…Post-ablation results can be evaluated best by contrast enhanced CT or MRI during the portal vein phase. Unsuccessful ablation can result in residual tumor and disease progression (65,66). In fact, recurrence following ablation can be as high as 20% to 60% (67,68).…”

Section: Treatment Methodsmentioning

confidence: 99%

“…There are, however, some limitations with CT imaging after cytotoxic treatments. As noted, post-chemotherapy liver steatosis causes lower attenuation in the image resulting in difficulties during the follow up which makes the MRI the better method to evaluate post treatment CRLM (65).…”

Section: Ctmentioning

confidence: 99%

Current state of the art imaging approaches for colorectal liver metastasis

Hazhirkarzar

Khoshpouri

Shaghaghi

et al. 2020

Hepatobiliary Surg Nutr

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One of the most common cancers worldwide, colorectal cancer (CRC) has been associated with significant morbidity and mortality and therefore represents an enormous burden to the health care system. Recent advances in CRC treatments have provided patients with primary and metastatic CRC a better long-term prognosis. The presence of synchronous or metachronous metastasis has been associated, however, with worse survival. The most common site of metastatic disease is the liver. A variety of treatment modalities aimed at targeting colorectal liver metastases (CRLM) has been demonstrated to improve the prognosis of these patients. Loco-regional approaches such as surgical resection and tumor ablation (operative and percutaneous) can provide patients with a chance at long-term disease control and even cure in select populations. Patient selection is important in defining the most suitable treatment option for CRLM in order to provide the best possible survival benefit while avoiding unnecessary interventions and adverse events.Medical imaging plays a crucial role in evaluating the characteristics of CRLMs and disease resectability.Size of tumors, proximity to adjacent anatomical structures, and volume of the unaffected liver are among the most important imaging parameters to determine the suitability of patients for surgical management or other appropriate treatment approaches. We herein provide a comprehensive overview of current-state-ofthe-art imaging in the management of CRLM, including staging, treatment planning, response and survival assessment, and post-treatment surveillance. Computed tomography (CT) scan and magnetic resonance imaging (MRI) are two most commonly used techniques, which can be used solely or in combination with functional imaging modalities such as positron emission tomography (PET) and diffusion weighted imaging (DWI). Providing up-to-date evidence on advantages and disadvantages of imaging modalities and tumor assessment criteria, the current review offers a practice guide to assist providers in choosing the most suitable imaging approach for patients with CRLM.

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Role of imaging for patients with colorectal hepatic metastases: what the radiologist needs to know

Cited by 9 publications

References 64 publications

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

Multidisciplinary management of liver metastases in patients with colorectal cancer: a consensus of SEOM, AEC, SEOR, SERVEI, and SEMNIM

Volumetric analysis at abdominal CT: oncologic and non-oncologic applications

Current state of the art imaging approaches for colorectal liver metastasis

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