Role of increased intestinal permeability in the development and progression of liver diseases

Abstract

The phenomenon of “leaky gut” or increased intestinal permeability has been actively studied over the past two decades. Its role has been proven in the development of irritable bowel syndrome and a number of other intestinal pathologies. At the same time, more and more information is accumulating on the effect of “leaky gut” on the occurrence and progression of liver diseases. This article presents a literature review of recent materials on the relationship between the intestine and the liver through the phenomenon of “leaky gut” and new potential points for therapeutic intervention.