2024
DOI: 10.1111/andr.13801
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Role of intra‐individual variation in the detection of thresholds for DFI and for misclassification rates: A retrospective analysis of 14,775 SCSA® tests

Preben Christensen,
Robert Fischer,
Wolfgang Schulze
et al.

Abstract: BackgroundSperm DNA damage is associated with reduced male fertility after natural conception and intrauterine insemination. However, the impact on in vitro fertilization (IVF) and especially intracytoplasmic sperm injection (ICSI) treatments is still unclear. Few studies have focused on the intra‐individual variation in DFI even though it may have an important role to play in terms of detection of thresholds and for misclassification rates.MethodsResults for Sperm Chromatin Structure Assay (SCSA®) tests perfo… Show more

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