Role of laparoscopy in the evaluation of the adnexa in patients with stage IV breast cancer

Quan, May Lynn; Fey, Jane; Eitan, Ram; Abu‐Rustum, Nadeem R.; Barakat, Richard R.; Borgen, Patrick I.; Gemignani, Mary L.

doi:10.1016/j.ygyno.2003.10.026

Cited by 12 publications

(6 citation statements)

References 12 publications

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“…Similarly, ovaries are also a rare site for breast cancer metastasis. 52 Oophorectomy may provide a beneficial therapeutic effect for premenopausal patients with hormone receptor-positive breast cancer irrespective of metastatic disease to the ovaries is present or not. There are limited data available regarding the local management of ovarian metastasis.…”

Section: Study Resultsmentioning

confidence: 99%

Role of Surgery in Metastatic Breast Cancer: Insights from a Narrative Review

Alghamdi¹,

Mahmood²

2023

BCTT

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Metastatic breast cancer is difficult to cure and has a worse prognosis with higher rates of mortality. Recently, breast surgery is believed to improve the survival rates among these women, but due to limited evidence, definite conclusions cannot be made. Therefore, we undertook this narrative review to synthesize the evidence from existing studies to assess the effectiveness of locoregional surgery and surgery of metastatic sites in improving the outcomes among women diagnosed with metastatic cancer disease along with the summary of current treatment guidelines. We reviewed PubMed and Embase and included both observational studies and randomized controlled trials (RCTs) that were published in English between 2000 and 2021. Outcomes were either survival, quality of life, toxicity related to local treatment assessed by mortality at the end of one month, progression-free survival, and breast cancer-specific survival. The main effect size assessed was hazard ratio with their 95% CIs. After literature search, we found 8 observational studies and 3 RCTs. The findings of the observational studies revealed that breast cancer surgery improves survival from 30% to 50% among women. However, findings from RCTs were mixed for local and distant progression survival. Surgery improved the local progression-free survival but worsened the distant progression-free survival. Besides, there was no effect of breast surgery on quality of life. Regarding the surgery of metastatic site, studies are complex with mixed findings and variation in survival depending upon the type of metastatic site and response to initial systematic therapy and other factors. Based on the existing mixed evidence, it is not possible to make firm and definite conclusions about the effectiveness of breast surgery in improving the survival or quality of life among women with metastatic breast cancer. In future, more RCTs are required with a larger sample size to confirm the findings of observational studies.

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Section: Study Resultsmentioning

confidence: 99%

Role of Surgery in Metastatic Breast Cancer: Insights from a Narrative Review

Alghamdi¹,

Mahmood²

2023

BCTT

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“…La probabilité de métastase va cependant en croissant avec la stadification initiale du cancer du sein. Ainsi, en cas de découverte d'une masse annexielle chez une patiente ayant un cancer du sein d'emblée métastatique, la probabilité s'inverse avec sept fois plus de métastase annexielle que de cancer primitif ovarien [6].…”

Section: Discussionunclassified

“…La laparoscopie permettra l'obtention des prélèvements biopsiques nécessaires, évi-tant éventuellement une laparotomie inutile en cas de processus annexiel bénin [6].…”

Section: Discussionunclassified

“…Lors de la découverte d'une masse annexielle chez une patiente ayant un antécédent de cancer du sein, la laparoscopie permettra l'obtention de prélèvements biopsiques nécessaires au diagnostique histologique [6], ainsi qu'une évaluation précise de l'extension abdominale et de la résécabilité des lésions métastatiques. Cette voie d'abord chirurgical pourrait également être proposée pour la résection de lésions métastatiques présentant une extension limitée.…”

Section: Discussionunclassified

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Métastase ovarienne du cancer du sein : à propos d’un cas. Rôle de la chirurgie cytoréductrice

Dubois¹,

Willems

Myant

2009

Journal de Gynécologie Obstétrique et Biologie de la Reproducti

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“…-L'exploration par coelioscopie de ces anomalies pelviennes isolées est bien sûr possible (17). Des métastases de cancer de sein sur orifices de trocart ont été toutefois été décrites et les précautions techniques doivent être les mêmes que pour toute coelioscopie en cas de suspicion de malignité.…”

Section: Exploration Chirurgicaleunclassified