2020
DOI: 10.1007/s00423-020-01980-2
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Role of lymphadenectomy in resectable pancreatic cancer

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Cited by 10 publications
(6 citation statements)
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“…Despite the fact that a few reports concluded that extended lymphadenectomies may provide a survival benefit, it is not clear if the extent of the lymphadenectomy affects survival or oncological results (14). However, a better stablished concept is that extended lymphadenectomies and the number of total LNs retrieval are at least crucial for proper tumor staging and survival prediction (prognostic information) (15).…”
Section: Discussionmentioning
confidence: 99%
“…Despite the fact that a few reports concluded that extended lymphadenectomies may provide a survival benefit, it is not clear if the extent of the lymphadenectomy affects survival or oncological results (14). However, a better stablished concept is that extended lymphadenectomies and the number of total LNs retrieval are at least crucial for proper tumor staging and survival prediction (prognostic information) (15).…”
Section: Discussionmentioning
confidence: 99%
“…PDAC patients have a high incidence of regional LN metastasis, with a positivity rate of up to 80% in those with resectable PDAC 25 . In this study, regional LN metastasis detected on preoperative imaging was a significant risk factor for early tumor recurrence, which is consistent with previous reports 13 , 15 .…”
Section: Discussionmentioning
confidence: 99%
“…In general, most randomized controlled trials (RCTs) to date didn't show any survival benefit supporting extended lymphadenectomy. It might even offer greater risk of postoperative morbidity, therefore, it is not recommended by most guidelines (59).…”
Section: Pd: Lymphadenectomymentioning
confidence: 99%