Role of Magnetic Resonance Imaging in Paediatric Epilepsy

M, Vijaya Kumari; S, Aswini Jyothi J; A, Suman Chandra; Pushpanjali, .; Jayalatha, N

doi:10.14260/jemds/2017/107

Cited by 1 publication

(1 citation statement)

References 16 publications

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“…The results showed that about half of patients 47% had normal MRI while 53% had a suspicious MRI abnormality including focal cortical dysplasia (FCD), abnormal signal in the temporal lobe as well as hippocampal volume loss. Contrasted to our results, Kumari et al(Kumari, Jyothi, Chandra, Pushpanjali, & Jayalatha, 2017) showed that 41% of epileptic patients had normal MRI while 59% of them had MRI findings including space occupying lesion/tumour in left parietal and temporal lobe, open-lip schizencephaly with cortical dysplasia and sturgeweber syndrome. The current work revealed that EEG localization of the studied patients 14% were generalized, 16% left frontal, 10% left temporooccipital, 13% temporal, 27% left temporal, 10% left temporocentral onset, 10% bilateral central onset.…”

Section: Discussioncontrasting

confidence: 99%

Holter study in Epileptic

Ahmed¹,

Marghany²,

Rahhal³

et al. 2022

ijhs

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Introduction: Heart rate variability have the potential to serve as a biomarker of SUDEP risk, allowing for increased counselling of patients and their families and serving as a valuable outcome measure for research aimed at developing drugs and therapies to reduce SUDEP risk. The sympathetic and parasympathetic modulatory activities of cardiac nerves result in a Holter test lasting less than 24 hours (a few minutes). Objective: for detection of heart rate variability and cardiac arrhythmias in epileptic children. Materials and methods: This cross-sectional study was carried out on 100 children with epilepsy. All patients were subjected to: history taking, full physical examination, echocardiography, 24 hours Holter, EEG, MRI brain, Standard 12-derivation ECG (including V4 R derivation). Results: There was a significant variability in HF, LF, LF/HF, RMSSD, SDNN and PNN50 among all time measurements throughout the day (P values <0.001). Heart rate variability was significantly worse in younger patients aged less than 10 years than others and was found comparable between males and females (P values > 0.05). Heart rate variability was significant in relation to EEG localization (All P<0.001) being worse in case of left temporal localization when compared to other types.

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Section: Discussioncontrasting

confidence: 99%