Role of major revision spine surgery in recurrent adjacent segment osteoporotic vertebral body fracture: a case report

Ghani, Imtiaz; Kroeber, Markus

doi:10.1007/s00402-012-1518-3

Cited by 2 publications

(2 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Vertebral osteoporotic fractures and their relapse may be influenced by genetic regulation, leading to an increased risk of disease occurrence, as well as changes in the maintenance time from recovery to recurrence (MTRR). [8,9] Interleukin-8 (IL8) is a chemokine produced primarily by mononuclear macrophages and other cell types such as epithelial cells, airway smooth muscle cells, and endothelial cells. [10] Interleukin-8 (IL-8), with a molecular weight of about 8KD, is initially a protein consisting of 99 amino acids, which is cleaved to form the active IL-8 isoform, which is a 77-amino acid peptide in nonimmune cells and a 72-amino acid peptide in monocytes and macrophages.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

The occurrence and development of vertebral osteoporosis regulated by IL-8

Zhu,

Ding,

Fan

et al. 2023

Medicine

View full text Add to dashboard Cite

Vertebral osteoporotic fracture is a common type of fracture, and the incidence is higher in the elderly. However, the relationship between vertebral osteoporotic fractures and interleukin-8 (IL-8) remains unclear. A total of 163 patients with osteoporotic vertebral fractures were recruited. Clinical and follow-up data were recorded, and the expression levels of IL1, MMP9, IL-8, and C-reactive protein in blood were measured. Pearson Chi-square test and Spearman correlation coefficient were used to analyze the relationship between vertebral osteoporotic fractures and related parameters. Univariate and multivariate logistic regression and univariate and multivariate Cox proportional hazards regression were used for further analysis. Pearson chi-square test, Spearman correlation coefficient and Logistic regression analysis showed that IL1 and IL-8 were significantly associated with vertebral osteoporotic fractures. Univariate Cox regression analysis showed that age and IL-8 expression level were significantly associated with maintenance time from recovery to recurrence of vertebral osteoporotic fractures. Multivariate Cox regression analysis showed that IL-8 expression level was significantly associated with maintenance time from recovery to recurrence of vertebral osteoporotic fractures. The higher the expression level of IL-8, the more likely it is to develop vertebral osteoporotic fracture, and the more likely it is to relapse in a short time.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%