Role of medicinal herbs in periodontal therapy: A systematic review

Abstract

A BSTRACT Aims and Objectives: The use of medicinal herbs to prevent gingival and periodontal diseases has become increasingly popular due to their anti-inflammatory and antioxidant properties. This systematic review aims to provide the current literature to validate the traditional use of medicinal herbs in the management of gingival and periodontal diseases. Materials and Methods: An online literature search was conducted to identify research papers published from 2010 to 2022 in three major scientific databases, PubMed, Scopus, and Web of Science, in June 2022. Original research studies, case reports, and systematic reviews on medicinal plants’ application in oral health care were selected to be included in this systematic review. Only high-quality articles identified in the quality assessment were included for evidence synthesis. Results: Initial keyword research yielded 726 free-text articles published between 2010 and 2022. Of these, 14 articles (8 research papers and 6 reviews) were included for evidence synthesis. The review’s findings indicate that the antibacterial property of medicinal plants is due to their alkaline nature and prevents plaque and calculus formation by maintaining acid–alkali balance in saliva. Various parts of medicinal plants help maintain periodontal health. Glycyrrhiza glabra , Ficus religiosa , and Plantago major effectively inhibit primary plaque colonizers and periodontal pathogens. Medicago sativa , Aloe barbadensis Miller, and Trifolium pratense have excellent applications in treating periodontal diseases. Mangifera indica , Pongamia pinnata , the husk of Cocos nucifera , the root of G. glabra and Curcuma longa , leaves of Psidium guajava and Azadirachta indica , fruits of Citrus medica and Punica granatum , Ocimum Moringa oleifera extract, and pomegranate peel extract can serve as a promising alternative in managing chronic gingivitis. Conclusion: The anti-inflammatory, antioxidant, antibacterial, and astringent action of extracts obtained from various parts of medicinal plants make them effective in reducing gingival and periodontal diseases. Herbal medicine may be a viable alternative to contemporary pharmaceuticals as an adjuvant to scaling and root planning procedures.

Preparation and Characterization of Ginseng Gel and In Vivo Evaluation of Its Clinical Efficacy in Generalized Chronic Gingivitis Patients

“…This has led to the use of herbal-based products such as neem, curcumin, tulsi, etc. in dentistry over the last few years especially due to factors such as fewer side effects, safe and environment friendly [13].…”

Potential of pomegranate mouthwash in inhibiting periodontopathogens bacteria development as alternative to halitosis therapy: A review

“…By inhibiting biofilm formation, the aggregation of other bacteria such as Porphyromonas gingivalis will be hampered from continuing the formation and maturation of dental plaque. This can suppress the breakdown of proteins into peptides, especially cysteine (Cys) and methionine (Met), which make a major contribution to bad breath odor/halitosis [22,[25][26][27].…”

Prospecção científica e tecnológica da Psidium guajava relacionada com a atividade anti-inflamatória e antimicrobiana no tratamento da periodontite

“…E a sua patogênese também envolve fatores imunogenéticos e o estilo de vida (Akkaoui et al, 2020;Shetty et al, 2020) 2019). Dessa forma, torna-se necessária a investigação de novos agentes quimioterápicos e os fitoquímicos naturais isolados através dos extratos das plantas têm se destacado (Pasupuleti et al, 2023;Shetty et al, 2020;Shetty et al, 2021).…”

“…A Psidium guajava, pertence à família Myrtaceae, popularmente conhecida como goiabeira, é uma planta medicinal descrita há muitos anos na literatura e famosa devido as suas propriedades antimicrobianas, antiinflamatórias, antioxidantes, antidiarreicas, antiparasitária, antitússicas, antigenotóxicas, antialérgicas, antimutagênicas, anticâncer, anti-hiperglicêmica e hepatoprotetora (Kumar, 2021;Pasupuleti et al, 2023;Shetty et al, 2018).…”

“…farmacêuticos contemporâneos como adjuvante(Pasupuleti et al, 2023). O artigo publicado em 2020 na revista Journal of Contemporary Dental Practice aborda a atividade antimicrobiana e efeito antiaderente de folhas da Psidium guajava em um modelo de biofilme cariogênico, sugerindo que esta substância pode ser efetivamente utilizada em produtos destinados a prevenir a cárie dentária e a doença periodontal(Millones-Gómez et al, 2020).…”