2022
DOI: 10.1186/s12935-022-02797-3
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Role of microRNA-34b-5p in cancer and injury: how does it work?

Abstract: MicroRNAs (miRNAs or miRs) are a class of noncoding single-stranded RNAs that can regulate gene expression by binding to the untranslated sequences at the 3 ' end of messenger RNAs. The microRNA-34 family is dysregulated in various human diseases. It is considered as a tumor-suppressive microRNA because of its synergistic effect with the well-known tumor suppressor p53. As a member of the miRNA-34 family, miR-34b-5p serves as a powerful regulator of a suite of cellular activities, including cell growth, multip… Show more

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Cited by 6 publications
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References 100 publications
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