Hypertensive local cerebral hemorrhage is the most common primary local cerebral hemorrhage in my country. The main clinical pathogenic reaction mechanism is acute hypertension and can cause tiny aneurysms in intracranial capillaries and intracranial vitreous vascular lesions. Minimally invasive removal is a surgery widely used in the treatment of hypertensive intracerebral hemorrhage in recent years, and is of great significance for improving the prognosis of patients. The purpose of this article is to study the application of spiral CT image post-processing technology to guide the hypertensive cerebral hemorrhage in minimally invasive removal. Through a study and investigation on spiral CT and hypertensive cerebral hemorrhage, the causes of hypertensive cerebral hemorrhage and the analysis of a series of complications that may occur after surgery. The results of the study showed that the hospital stay of hypertensive cerebral hemorrhage patients with minimally invasive removal surgery was 14 days, the amount of surgical bleeding was 54.82ml, and the operation time was 2.42 hours, while the hospital stay of ordinary cerebral hemorrhage patients with conventional clearance surgery was 24 days. The operation bleeding volume was 412.73ml, and the operation time was 4.23 hours. This shows that the application guidance of spiral CT image post-processing technology and the practical application prospect of hypertensive cerebral hemorrhage in clinical minimally invasive removal technology are very good.